Chunxiu YUAN

Professional Title: Professor

Education: PhD

Supervisor Category: Master Supervisor

Research Fields: Pathogen Biology and Detection Preparation of Waterfowl Viral Disease

1. Introduction

Chunxiu Yuan, PhD, Professor, Master Supervisor. Since 1998 to 2019, she has been engaged in the research of schistosoma development biology, presided over two projects funded by the National Natural Science Foundation of China, won the second prize of Shanghai Science and Technology Progress Award and the first prize of the Chinese Academy of Agricultural Sciences (ranked fourth), and trained (including joint training) 1 doctoral student and 15 master students. Since August 2019, due to the need of discipline development, she has transferred to Waterfowl Viral Disease and Animal Influenza Prevention and Control Team of the Institute, and is currently engaged in basic and applied research on pathogen biology and detection preparation of waterfowl viral disease.

2. Contact Information

Tel：021-34293604

Email：yuanchx@shvri.ac.cn

3. Representative Publications

(1). Wu M, Zhang Z, Su X, Lu H, Li X, Yuan C, Liu Q, Teng Q, Geri L, Li Z. Biological Characteristics of Infectious Laryngotracheitis Viruses Isolated in China. Viruses. 2022 May 31;14(6):1200.

(2). Su X, Shuo D, Luo Y, Pan X, Yan D, Li X, Lin W, Huang D, Yang J, Yuan C, LiuQ, Teng Q, Li Z. An Emerging Duck Egg-Reducing Syndrome Caused by a Novel Picornavirus Containing Seven Putative 2A Peptides. Viruses. 2022 Apr29;14(5):932.

(3). Yan D, Li X, Wang Z, Liu X, Dong X, Fu R, Su X, Xu B, Teng Q, Yuan C, Zhang Z, Liu Q, Li Z. The emergence of a disease caused by a mosquito origin Cluster3.2 Tembusu virus in chickens in China. Vet Microbiol. 2022 Sep; 272:109500.

(4). Xu B, Liu X, Yan D, Teng Q, Yuan C, Zhang Z, Liu Q, Li Z. Generation and characterization of chimeric Tembusu viruses containing pre-membrane and envelope genes of Japanese encephalitis virus. Front Microbiol. 2023 Jun22; 14:1140141.

(5). Xu J, Feng X, Jia Y, Hong Y, Li H, Lu K, Lin J, Yuan C*, Song M. Characterization and expression pattern of a novel Frizzled 8 receptor gene in Schistosoma japonicum. Parasitol Int. 2017 Oct; 66(5):522-528.

(6). Ye Z, Xu J, Feng X, Jia Y, Fu Z, Hong Y, Li H, Lu K, Lin J, Song M, Wang L, Yuan C*. Spatiotemporal expression pattern of Sjfz7 and its expression comparison with other frizzled family genes in developmental stages of Schistosoma japonicum. Gene Expr Patterns. 2019 Jun; 32:44-52.

(7). Luo X, Shi X, Yuan C, Ai M, Ge C, Hu M, Feng X, Yang X. Genome-wide SNP analysis using 2b-RAD sequencing identifies the candidate genes putatively associated with resistance to ivermectin in Haemonchus contortus. Parasit Vectors. 2017 Jan 17; 10(1):31.

(8). Wang X, Li H, Qi X, Shi Y, Xia Y, Yang J, Yuan C*, Feng X, Lin J. Characterization and expression of a novel Frizzled 9 gene in Schistosoma japonicum. Gene Expr Patterns. 2011 Mar-Apr; 11(3-4):263-70.

(9). Ta N, Feng X, Deng L, Fu Z, Hong Y, Liu J, Li H, Lu K, Lin J, Yuan C*. Characterization and expression analysis of Wnt5 in Schistosoma japonicum at different developmental stages. Parasitol Res. 2015 Sep; 114(9):3261-9.

(10).  Wnt4, the first member of the Wnt family identified in Schistosoma japonicum, regulates worm development by the canonical pathway. Li HF, Wang XB, Jin YP, Xia YX, Feng XG, Yang JM, Qi XY, Yuan CX*, Lin JJ. Parasitol Res. 2010 Sep;107(4):795-805.

4. Granted National Invention Patents and Standards

(1). The β-catenin gene and protein of Schistosoma japonicum and their application, 2010, Chinese invention patent, CN201010239053.0;

(2). The Wnt5 gene and protein of Schistosoma japonicum and their application, 2013, Chinese invention patent, CN201310199173.6;

(3). The use of cyclophosphamide or its derivatives, 2018, Chinese invention patent, N110856722A.

5. Rewards and Achievements

(1). Screening, analysis and functional studies of genes related to the growth and development of Schistosoma japonicum, June 2008, the second prize of the scientific and technological achievements of the Chinese Academy of Agricultural Sciences, the fourth completer;

(2). Screening of candidate antigen genes and protection effect of Schistosoma japonicum, October 2008, the second prize of Shanghai Science and Technology Progress Award, the fourth completer.