Home Teams and Professors Innovation Teams Risk Early Warning, Prevention and Control of Bacterial Infectious Diseases in Livestock and Poultry

Introduction of Chief Scientist

Shaohui WANG

Professional Title: Professor

Education: PhD

Supervisor Category: Doctoral Supervisor

Research Fields: Molecular epidemiology, pathogenic mechanism and novel vaccines, diagnostic technologies of important zoonotic and animal bacterial pathogens, including Brucella, Escherichia coli, Salmonella, Mycoplasma, Riemerella anatipestifer, Clostridium perfringens and Mycobacterium; Antibiotic resistance, transmission mechanism and alternative control strategy for multidrug-resistant bacterial infections, including bacteriophage, probiotics, antimicrobial peptides.

1. Introduction

Shaohui Wang, Ph. D., Professor, Doctoral supervisor, Chief-scientist of Innovation Team of Animal Bacterial Infectious Diseases, Deputy director of Department of Animal Public Health, Shanghai Veterinary Research Institute (SHVRI), Chinese Academy of Agricultural Sciences (CAAS). He has been recognized as the Shanghai Eastern Talent, Shanghai Pujiang Talent, Young Talent of Chinese Academy of Agricultural Sciences, Leading Talent of Minhang District. He serves as editorial board member of multiple journals, including Journal of Integrative Agriculture, BMC Microbiology, BMC Veterinary Science, Frontiers in Microbiology, Frontiers in Veterinary Science, Veterinary Sciences, Frontiers in Cellular and Infection Microbiology.

He has been engaged in the research of important zoonotic and animal bacterial diseases. His work focus on the molecular epidemiology, antibiotic resistance pathogenic mechanism, novel vaccines, diagnostic technologies and alternative control strategy for important animal bacterial diseases. He hosted over 10 national and provincial project fundings. He has published more than 90 SCI papers, 2 books and 32 authorized invention patents. He has received numerous awards, including the Second prize of Excellent Innovative Achievements of Shanghai, Second prize of Scientific and technological achievements of Chinese Academy of Agricultural Sciences (CAAS), etc.

2. Contact Information

Tel: +86-21-34293412

Cell: +86-15821927863

E-mail: shwang@shvri.ac.cn; shwang0827@126.com

3. Awards

[1]. Eastern Talent Plan Project of Shanghai;

[2]. Shanghai Pujiang Program Fellowship;

[3]. Young Talents of Chinese Academy of Agricultural Sciences (CAAS);

[4]. Leading Talent of Minhang District, Shanghai;

[5]. Second prize of Scientific and technological achievements of Chinese Academy of Agricultural Sciences (CAAS);

[6]. Second prize of Excellent Innovative Achievements of Shanghai;

[7]. Gold Award of Excellent Invention of Shanghai;

[8]. First prize of Excellent Innovative Achievements of Minhang District, Shanghai;

[9]. Third prize of Science and Technology awards of Pudong District, Shanghai

[10]. Excellent staff of Shanghai Veterinary Research Institute (SHVRI), Chinese Academy of Agricultural Sciences (CAAS) (2013, 2014, 2016, 2019 and 2022)

4. Selected Publications

(1) Lei Deng*, Shaohui Wang*. Colonization resistance: the role of gut microbiota in preventing Salmonella invasion and infection. Gut Microbes, 2024, 16(1): 2424914.

(2) Xinyu Wang, Hong Zhu, Jiangang Hu, Beibei Zhang, Weiqi Guo, Zhiyang Wang, Di Wang, Jingjing Qi, Mingxing Tian, Yanqing Bao, Fusheng Si*, Shaohui Wang*. Genetic distribution, characterization, and function of Escherichia coli type III secretion system 2 (ETT2). iScience, 2024, 27(5): 109763.

(3) Weiqi Guo, Di Wang, Xinyu Wang, Zhiyang Wang, Hong Zhu, Jiangang Hu, Beibei Zhang, Jingjing Qi, Mingxing Tian, Yanqing Bao, Na Li, Wanjiang Zhang*, Shaohui Wang*. Identification and characterization of a plasmid co-harboring blaCTX-M-55 and blaTEM-141 in Escherichia albertii from broiler in China. Journal of Integrative Agriculture, 2025, 24(8): 3212-3221.

(4) Luru Zhao, Weiqi Guo, Bin Zhang, Xiaochuan Tang, Yinan Liu, Jingyi Liang, Qi Wu, Yanqing Bao, Mingxing Tian, Shaohui Wang*, Jingjing Qi*. Identification and efficacy assessment of novel immunoprotective antigens from Mycoplasma synoviae for vaccine development. NPJ Vaccines, 2025, 11(1): 32.

(5) Zhiyang Wang, Xinyu Wang, Weiqi Guo, Di Wang, Jiangang Hu, Beibei Zhang, Jingjing Qi, Mingxing Tian, Yanqing Bao, Haihua Li*, Shaohui Wang*. Identification and Genomic Analyses of a Multidrug Resistant Avian Pathogenic Escherichia coli Coharboring mcr-1, blaTEM-176 and blaCTX-M-14 Genes. Transboundary and Emerging Diseases, 2024: 9332418.

(6) Luru Zhao, Xiaochuan Tang, Weiqi Guo, Bin Zhang, Haoheng Peng, Lijun Ye, Yinan Liu, Jingyi Liang, Mingxing Tian, Yanqing Bao, Jingjing Qi*, Shaohui Wang*. Using a novel gene site to develop a duplex real-time TaqMan MGB probe PCR method for the SNP detection and differentiation between the MS-H live vaccine strain and wild-type Mycoplasma synoviae strains. Poultry Science, 2025, 104(5): 105011.

(7) Shuangyang Li, Jiangang Hu, Chang Liu, Zizhu Lin, Haoheng Peng, Beibei Zhang, Xinyu Wang, Weiqi Guo, Jingjing Qi, Mingxing Tian, Yanqing Bao, Guangdong Zhang, Yuxiang Shi*, Shaohui Wang*. Inner membrane protein TolA facilitates the antibiotic resistance, environment adaptability, biofilm formation and virulence of avian pathogenic Escherichia coli. Journal of Integrative Agriculture, 2025. https://doi.org/ 10.1016/j.jia.2025.02.012.

(8) Xinyu Wang, Weiqi Guo, Jiangang Hu, Beibei Zhang, Jingjing Qi, Mingxing Tian, Yanqing Bao, Lei Deng, Shaohui Wang*. The deubiquitinase ElaD is present in the majority of Escherichia coli strains. Frontiers in Microbiology, 2025, 16: 1681308.

(9) Yong Wang, Mengsi Li, Xinmei Yang, Yi Yin, Jinyue Liu, Jing Qu, Yanqing Bao, Jingjing Qi, Xiangan Han, Shaohui Wang*, Mingxing Tian*. The LysR-family transcriptional regulator VtlR coordinates carbon metabolism, oxidative and nitrosative stress resistance, and virulence in Brucella melitensis. Veterinary Research, 2025, 56(1):214.

(10) Yaodong Zhang, Yao Wang, Hong Zhu, Zhengfei Yi, Dossêh Jean Apôtre Afayibo, Chenglin Tao, Tao Li, Mingxing Tian, Jingjing Qi, Chan Ding, Shengqing Yu*, Shaohui Wang*. DctR contributes to the virulence of avian pathogenic Escherichia coli through regulating the type Ⅲ secretion system 2 expression. Veterinary Research, 2021, 52(1): 101.