Yanqing BAO
Professional Title: Professor
Education: PhD
Supervisor Category: Master Supervisor
Research Fields: investigate molecular mechanism of bacterial pathogenesis
1. Contact Information
Tel: 021-34293412
E-mail: ybao@shvri.ac.cn
2. Bio
2007-2011 BS in Veterinary Medicine, Yanghzou University
2011-2014 MS in Preventive Veterinary Medicine, Yanghzou University
2014-2017 PhD in Preventive Veterinary Medicine, Chinese Academy of Agriculture Science
2017-2021 PostDoc, The University of Texas at El Paso
3. Expertise
Dr. Bao's primary research interest is to investigate molecular mechanism of bacterial pathogenesis, especially focusing on identification and functions of bacterial virulence related genes. In past years, Dr Bao have been characterizing genes that regulate intracellular survival of Brucella, functional mechanism and interaction proteins of Mycobacteria virulence factor EsxA. Also, he is exploring the application of AI image recognition methods in bacteria infection detection.
4. Publication
(1) Zuo, W.; Yang, D.; Wu, X.; Zhang, B.; Wang, X.; Hu, J.; Qi, J.; Tian, M.; Bao, Y.; Wang, S. The aroA and luxS Double-Gene Mutant Strain Has Potential to Be a Live Attenuated Vaccine against Salmonella Typhimurium. Vaccines (Basel) 2024, 12 (2). DOI: 10.3390/vaccines12020162.
(2) Zuo, W.; Tian, M.; Qi, J.; Zhang, G.; Hu, J.; Wang, S.; Bao, Y. The functions of EF-hand proteins from host and zoonotic pathogens. Microbes Infect 2023, 105276. DOI: 10.1016/j.micinf.2023.105276.
(3) Bao, Y.; Wang, L.; Sun, J. A Small Protein but with Diverse Roles: A Review of EsxA in Mycobacterium-Host Interaction. Cells 2021, 10 (7). DOI: 10.3390/cells10071645.
(4) Bao, Y.; Wang, L.; Sun, J. Post-translational knockdown and post-secretional modification of EsxA determine contribution of EsxA membrane permeabilizing activity for mycobacterial intracellular survival. Virulence 2021, 12 (1), 312-328. DOI: 10.1080/21505594.2020.1867438.
(5) Bao, Y.; Zhao, X.; Wang, L.; Qian, W.; Sun, J. Morphology-based classification of mycobacteria-infected macrophages with convolutional neural network: reveal EsxA-induced morphologic changes indistinguishable by naked eyes. Transl Res 2019, 212, 1-13. DOI: 10.1016/j.trsl.2019.06.001.
(6) Tian, M.; Bao, Y.; Li, P.; Hu, H.; Ding, C.; Wang, S.; Li, T.; Qi, J.; Wang, X.; Yu, S. The putative amino acid ABC transporter substrate-binding protein AapJ2 is necessary for Brucella virulence at the early stage of infection in a mouse model. Veterinary research 2018, 49 (1), 1-11.
(7) Bao, Y.; Tian, M.; Li, P.; Liu, J.; Ding, C.; Yu, S. Characterization of Brucella abortus mutant strain Δ22915, a potential vaccine candidate. Vet Res 2017, 48 (1), 17. DOI: 10.1186/s13567-017-0422-9.