Guoxin LI
Professional Title: Professor
Education: PhD
Supervisor Category: Doctoral Supervisor
Research Fields: diagnosis and prevention of animal infectious diseases
1. Introduction
Mr. Li obtained BSc degree in Veterinary Medicine from Heilongjiang Bayi Agricultural University, China in 1997; an MSc degree in Basic Veterinary Medicine from Northeast Agricultural University, China in 2005; and a PhD degree in Preventive Veterinary Medicine from Northeast Agricultural university in 2008. Mr. Li worked at Institute of Veterinary Medicine, Heilongjiang Academy of Agricultural Sciences from 1997 to 2008. Since July 2008, Mr. Li has been employed at Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences. Li’s research group is focused on: 1) Epidemiology of major swine infectious diseases; 2) Development of diagnosis, antiviral agents and vaccines for pseudorabies virus, coronavirus, porcine reproductive and respiratory syndrome virus, classical swine fever virus, emerging and reemerging animal viruses. Li has published more than 20 research papers in the international journals and developed 2 vaccines that has been wildly used for preventing and control animal diseases in China.
2. Contact Information
E-mail: guoxinli@shvri.ac.cn
3. Recent Publications
(1). Yuanhong Wang†, Junhan Song†, Xiaoying Deng, Junna Wang, Miao Zhang, Liu Yun, Pan Tang, Huili Liu, Yanjun Zhou, Guangzhi Tong, Guoxin Li*, Lingxue Yu*. Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) of Porcine deltacoronavirus (PDCoV) Elicit Robust Protective Immune Responses in mice. Frontiers in Immunology. 10.3389/fimmu.2024.1328266.
(2). Yuanhong Wang，Yun Liu , Junna Wang , Miao Zhang, Xiaoying Deng , Junhan Song , Jie Zhu, Lingxue Yu*, Guoxin Li*, Guangqing Liu*. An adenovirus-vectored vaccine based on the N protein of feline coronavirus elicit robust protective immune responses. Antiviral Research. 2024.10.1016/j.antiviral.2024.105825.
(3). Liwei Li#, Sina Qiao#, Jiachen Liu, Yanjun Zhou, Wu Tong, Shishan Dong, Changlong Liu, Yifeng Jiang, Ziqiang Guo, Haihong Zheng, Ran Zhao, Guangzhi Tong, Guoxin Li*, Fei Gao*. A highly efficient indirect ELISA and monoclonal antibody established against African swine fever virus pK205R. Frontiers in Immunology. 2023 Jan 9:13:1103166.
(4). Yifeng Jiang#, Fei Gao#, Liwei Li, Yanjun Zhou, Wu Tong, Lingxue Yu, Yujiao Zhang, Kuan Zhao, Haojie Zhu, Guoxin Li*, Guangzhi Tong*. The rPRRSV-E2 strain exhibited a low level of potential risk for virulence reversion. Frontiers in Veterinary Science. 2023 Mar 7:10:1128863.
(5). Jingjing Xu, Xuefei Cheng, Yuting Liu, Xinling Fu, Wu Tong, Hao Zheng, Guangzhi Tong, Fei Gao*, Guoxin Li*. Psudorabies virus UL16 protein influence the inhibition of LRPPRC for the viral proliferation. Veterinary Microbiology. 2022 Feb; 265:109327.
(6). Jing-Jing Xu, Xue-Fei Cheng, Ji-Qiang Wu, Hao Zheng, Wu Tong, Xiaoyong Chen, Chao Ye, Yuting Liu, Haojie Zhu, Xinling Fu, Yifeng Jiang, Ning Kong, Guangzhi Tong, Fei Gao*, Guoxin Li*. Pseudorabies virus pUL16 assists the nuclear import of VP26 through protein-protein interaction. Veterinary Microbiology. 2021 Jun: 257:109080.
(7). Jing-Jing Xu, Fei Gao, Ji-Qiang Wu, Hao Zheng, Wu Tong, Xue-Fei Cheng, Yuting Liu, Haojie Zhu, Xinling Fu, Yifeng Jiang, Liwei Li, Ning Kong, Guoxin Li*, Guangzhi Tong*. Characterization of Nucleocytoplasmic Shuttling of Pseudorabies Virus Protein UL46. Frontiers in Veterinary Science. 2020 Aug 21:7:484.
(8). Jing-Jing Xu, Ji-Qiang Wu, Xue-Fei Cheng, Wu Tong, Hao Zheng, Hao-Jie Zhu, Yu-Ting Liu, Yi-Feng Jiang, Fei Gao, Hai Yu, Tong-Ling Shan, Guo-Xin Li*, Guang-Zhi Tong*. Identification of two novel epitopes targeting glycoprotein E of pseudorabies virus using monoclonal antibodies. Biochemical and Biophysical Research Communications. 2019.519(2):330-336.