Beibei LI

Professional Title: Professor

Education: PhD

Supervisor Category: Doctoral Supervisor

Research Fields: Antimicrobial resistance of animal-origin bacteria, molecular mechanisms of transmission of important resistant genes, and rapid detection technologies for bacterial pathogens and antimicrobial resistance.

1. Introduction

LI Beibei, Ph.D., Professor, doctoral supervisor, part-time doctoral supervisor at Xinjiang Agricultural University. He is a Shanghai Young Science and Technology Rising Star and a member of the Youth Talent Development Program in the Chinese Academy of Agricultural Sciences. He has long been engaged in research on the epidemiology of animal-origin bacterial antimicrobial resistance, identification new resistant genes, molecular mechanisms of transmission of important resistant genes, and development of rapid detection technologies of bacterial pathogens and antimicrobial resistance. He has been the principal investigator for 7 national and provincial-level projects and has supervised the training of 1 doctoral student and 6 master’s students. He has published over 30 papers in international journals, including “Journal of Antimicrobial Chemotherapy” “Plos Pathogens” and “Veterinary Microbiology”. He has also published one monograph and obtained 4 patents.

2. Contact information

Tel: 021-34293635

Email: lbb@shvri.ac.cn

3. Representative works

[1]. Xin Wang, Zhuanchang Wu, Yuming Li, Yifan Yang, Changguang Xiao, Xiqian Liu, Xiao Xiang, Jianchao Wei, Donghua Shao, Ke Liu, Xufang Deng, Jiaqiang Wu , Yafeng Qiu, Beibei Li※, Zhiyong Ma※. p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication. Plos pathogens 2020 16, e1009035, doi:10.1371/journal.ppat.1009035. (Corresponding author)

[2]. Huiyong Xuan, Xiaohui Yao, Ruyi Pan, Yun Gao, Jianchao Wei, Donghua Shao, Ke Liu, Zongjie Li, Yafeng Qiu, Zhiyong Ma, Beibei Li※, Lining Xia※. (2021). Antimicrobial resistance in Enterococcus faecium and Enterococcus faecalis isolates of swine origin from eighteen provinces in China. Journal of Veterinary Medical Science, advpub. doi: 10.1292/jvms.21-0413 (Corresponding author).

[3]. Yun Gao , Lining Xia , Ruyi Pan , Huiyong Xuan , Hongdou Guo , Qiangqiang Song , Jianchao Wei , Donghua Shao , Ke Liu , Zongjie Li , Yafeng Qiu , Zhiyong Ma※, Beibei. Li※. Identification of mcr-1 and a novel chloramphenicol resistance gene catT on an integrative and conjugative element in an Actinobacillus strain of swine origin. Veterinary Microbiology 2021 254, 108983. (Corresponding author)

[4]. Huixian Tong，Juxiang Liu，Xiaohui Yao，Haiyan Jia，Jianchao Wei， Donghua Shao， Ke Liu， Yafeng Qiu， Zhiyong Ma※， Beibei Li※ High carriage rate of mcr-1 and antimicrobial resistance profiles of mcr-1-positive Escherichia coli isolates in swine faecal samples collected from eighteen provinces in China. Veterinary microbiology 2018, 225, 53-57. (Corresponding author)

[5]. Jianchao Wei,  Xin Wang,  Junjie Zhang,  Shuang Guo,  Linlin Pang,  Kun Shi,  Ke Liu,  Donghua Shao,  Yafeng Qiu,  Lihong Liu,  Frederik Widén,  Beibei Li※, Zhiyong Ma※. Partial cross-protection between Japanese encephalitis virus genotype I and III in mice. PLoS neglected tropical diseases, 2019, 13(8): e0007601. (Corresponding author)

[6]. Li Chenxi, Di Di, Wang Xin, Xia Qiqi, Wahaab Abdul, Anwar Muhammad Naveed, Li Zongjie, Liu Ke, Shao Donghua, Qiu Yafeng， Beibei Li※, Zhiyong Ma※: Duck karyopherin α4 (duKPNA4) is involved in type I interferon expression and the antiviral response against Japanese encephalitis virus. Developmental & Comparative Immunology 2020, 104:103535. (Corresponding author)

[7]. Beili Huan, Ke Liu, Yuming Li, Jianchao Wei, Donghua Shao, Yuanyuan Shi, Yafeng Qiu, Beibei Li※ and Zhiyong Ma※. Porcine serum amyloid A3 is expressed in extrahepatic tissues and facilitates viral replication during porcine respiratory and reproductive syndrome virus infection. Developmental and comparative immunology. 2018;79:51-58. (Co-corresponding author)

[8]. Jinpeng Xu， Haiyan Jia， Guanghui Cui， Huixian Tong， Jianchao Wei， Donghua Shao， Ke Liu， Yafeng Qiu， Beibei Li※ and ZhiyongMa※. ICEAplChn1, a novel SXT/R391 integrative conjugative element (ICE), carrying multiple antibiotic resistance genes in Actinobacillus pleuropneumoniae, Veterinary Microbiology, 2018. 220:18-23. (Co-corresponding author)

[9]. Beibei Li, Jiannan Yao, Jinachao Wei, Donghua Shao, Ke Liu, Yafeng Qiu and Zhiyong Ma. Characterization of fluoroquinolone resistance in methicillin-resistant Staphylococcus aureus of human and pig origin. Journal of global antimicrobial resistance. 2018. 12: 77-78.

[10]. Beibei Li, Licai Ma, Yingli Li, Haiyan, Jia, Jianchao Wei, Donghua Shao, Ke Liu, Yuanyuan Shi, Yafeng Qiu and Zhiyong Ma. Antimicrobial Resistance of Campylobacter Species Isolated from Broilers in Live Bird Markets in Shanghai, China. Foodborne pathogens and disease. 2017. 14: 96-102.

4. Patent standards

[1] A real-time fluorescent quantitative RT-PCR method and its reagent kit for the detection of Z/S subtypes of Ebola virus in a single step. Authorization time: 2017.03.22. Chinese patent number: ZL201110312855.

[2] A composition for the treatment of anti-Japanese encephalitis virus infection and its application. Authorization time: 2018.10.23. Chinese patent number: ZL201510391532.

[3] SiRNA targeting influenza virus-related genes and its application. Authorization time:2018.08.31. Chinese patent number: ZL201610139670.

[4] Recombinant vector and its application in the preparation or screening of anti-influenza drugs. Authorization time:2019.04.02. Chinese patent number: ZL201610141142.