Hongyu HAN

Professional Title: Professor

Education: PhD

Supervisor Category: Doctoral Supervisor

Research Fields: Animal and poultry protozoosis, animal coccidiosis epidemiology, immunology and drug control, etc.

1. Introduction

Hongyu Han, ph. D., professor, Ph. D./Master Supervisor, Leading Talents in Minhang District, Shanghai, the executive director of the Protozoology branch of the China Zoological Society and the vice chairman of the Shanghai Zoological Society.  Researches focused on Animal and poultry protozoosis, animal coccidiosis epidemiology, immunology and drug control, etc.

Hosted more than 20 projects, including the National Natural Science Foundation of China, the national key research and development projects, and the Shanghai Natural Fund, and so on. Trained more than 2 doctoral students and 15 master students. Published 12 books and more than 100 papers in International Journal for Parasitology: Drugs and Drug Resistance, Frontiers in Cellular and Infection Microbiology, Parasite & Vectors, ect. Obtained 5 authorized national invention patents.

2. Contact Information

Tel: 18939889279, 13917408252

E-mail: hhysh@shvri.ac.cn

3. Selected Publications

[1] Huanzhi Zhao, Hui Dong, Qiping Zhao, Shunhai Zhu, Liushu Jia, Sishi Zhang, Qian Feng, Yu Yu, Jinwen Wang, Bing Huang, Hongyu Han^*. Integrated application of transcriptomics and metabolomics provides insight into the mechanism of  Eimeria tenella  resistance to maduramycin. International Journal for Parasitology: Drugs and Drug Resistance. Volume 24, April 2024, 100526.

[2] Yu Yu, Wenhao Huang, Qingjie Wang, Hui Dong, Qiping Zhao, Shunhai Zhu, Bing Huang, Hongyu Han^*. Molecular characterization and analysis of drug resistance-associated protein enolase 2 of  Eimeria tenella . International Journal for Parasitology: Drugs and Drug Resistance. (2023) 21 81–90. doi: 10.1016/j.ijpddr.2023.01.004.

[3] Ke Xiao, Qiping Zhao, Haixia Wang, Shunhai Zhu, Hui Dong, Bing Huang, Hongyu Han^*. Molecular characterization of methionine aminopeptidase1 from  Eimeria tenella . European Journal of Protistology. (2023) 90:126012. doi: 10.1016/j.ejop.2023.126012. 

[4] Wenhao Huang, Shunhai Zhu, Ting Chen, Qiping Zhao, Hui Dong, Bing Huang, Yawen Yao, Zhan Liu, Yu Yu, Hongyu Han*. Molecular characterization of glyceraldehyde-3-phosphate dehydrogenase from  Eimeria   tenella . Parasitology Research. (2022) 121(6):1749-1760. doi: 10.1007/s00436-022-07508-5.

[5] Shanshan Liang, Qiping Zhao, Yonggang Ye, Shunhai Zhu, Hui Dong, Yu Yu, Bing Huang, Hongyu Han*. Characteristics analyses of  Eimeria tenella  14-3-3 protein and verification of its interaction with calcium-dependent protein kinase 4. European Journal of Protistology, (2022) 85,125895. doi: 10.1016/j.ejop.2022.125895.

[6] Huanzhi Zhao, Cong Li, Shunhai Zhu, Qiping Zhao, Hui Dong, Bing Huang, Hongyu Han*. Molecular characterization and immune protection by cystathionine β-synthase from Eimeria tenella. The Journal of Eukaryotic Microbiology. (2022)，69(2):e12876. doi: 10.1111/jeu.12876.

[7] Shanshan Liang, Hui Dong, Shunhai Zhu, Qiping Zhao, Bing Huang, Yu Yu, Qingjie Wang, Haixia Wang, Shuilan Yu, Hongyu Han*.  Eimeria tenella  Translation Initiation Factor eIF-5A That Interacts with Calcium-Dependent Protein Kinase 4 Is Involved in Host Cell Invasion. Frontiers in Cellular and Infection Microbiology，(2021),10:602049.doi: 10.3389/fcimb.2020.602049.

[8] Yu Yu , Hui Dong, Qiping Zhao, Shunhai Zhu, Shanshan Liang, Qingjie Wang, Haixia Wang, Shuilan Yu, Bing Huang, Hongyu Han^*.  Molecular characterization and analysis of the ATPase ASNA1 homolog gene of  Eimeria tenella  in a drug sensitive strain and drug resistant strains. International Journal for Parasitology:  Drugs and Drug Resistance, 2021 15:115-125. doi: 10.1016/j.ijpddr.2021.02.005.

[9] Haixia Wang , Qiping Zhao, Shunhai Zhu, Hui Dong Shuilan Yu, Qingjie Wang, Yu Yu, Shanshan Liang, Huanzhi Zhao, Bing Huang , Hongyu Han*. Molecular characterization and functional analysis of  Eimeria tenella  citrate synthase，Parasitology Research， 2021，120(3):1025-1035. doi: 10.1007/s00436-020-07014-6.

[10] Cong Li, Qiping Zhao, Shunhai Zhu, Qingjie Wang, Haixia Wang, Shuilan Yu,Yu Yu, Shashan Liang, Huanzhi Zhao, Bing Huang, Hui Dong* and Hongyu Han*.  Eimeria tenella  E  imeria -specific protein that interacts with apical membrane antigen 1 (EtAMA1)is involved in host cell invasion. Parasites & Vectors. 2020, 13(1):373. doi: 10.1186/s13071-020-04229-5.

[11] Yu Yu, Qiping Zhao, Shunhai Zhu, Hui Dong , Bing Huang, Shanshan Liang, Qingjie Wang , Haixia Wang , Shuilan Yu, Hongyu Han^*. Molecular characterization of serine/threonine protein phosphatase of  Eimeria tenella . The Journal of Eukaryotic Microbiology，2020，67(5):510-520. https://doi.org/10.1111/jeu.12798.

4. Patents and National Standard

[1] Diagnostic techniques for animal coccidiosis，GB/T18647-2020，Standardization Administration of the People’s Republic of China.

[2] A molecular marker of Eimeria tenella sensitive strain and drug resistant strain and its application. Patent No.: 202010427465.0. Authorized date: 11/08/2022.

[3] An AN1-like zinc finger protein of Eimeria tenella and its application in the inhibition of Eimeria invasion. Patent No.: 201910428572.2. Authorized date: 08/02/2022.

[4] A CHP317 gene and vaccine for controlling chicken coccidiosis and its preparation method thereof. Patent No.: ZL 201510933893.X. Authorized date: 27/11/2018.

[5] A cystathionine β synthase  gene and vaccine for controlling chicken coccidiosis and its preparation method thereof. Patent No.: ZL 201510933891.0. Authorized date: 27/11/2018.