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Introduction

Zongyan CHEN

Professional Title: Associate Professor

Education: PhD

Mentor category: Master Supervisor

Research Fields: Identification of molecular determinants of reovirus/IBDV virulence; Identification of the mechanisms of reovirus pathogenesis; Molecular characterization of new and emerging waterflow diseases; Vaccine Development

1. Contact Information

Phone: 021-34293426

Fax: 021-54082828

E-mail:zychen@shvri.ac.cn

2. Professional Training and Experience

2008-Pres. Faculty, Associate Professor

2014-2015. Guest Investigator, Department of Veterinary Medicine, Virginia-Maryland Regional College of Veterinary Medicine, College Park

2003-2008. Ph.D. in Avian Diseases and Molecular Biology, Sichuan Agricultural University, Yaan, China

3. Publications  

(1). Wu Qiaomei, Ding Mingyang, Li Chuanfeng, Liu Guangqing, Chen Zongyan*. Construction and characterization of an infectious molecular clone of novel duck reovirus.  Journal of General Virology,2018 ;99(4) 449–4561.

(2). Dawei Xu, Chuanfeng Li, Guangqing Liu, Zongyan Chen*, Renyong Jia*. Generation and evaluation of a recombinant goose origin Newcastle disease virus expressing Cap protein of goose origin avastrovirus as a bivalent vaccine in goslings. Poultry Science, 2019(98):4426–4432.

(3). Xiaxia Du, Rong Xiao, Hualin Fu , Zhixiang Yuan , Wei Zhang , Lizi Yin , Changliang He , Chuanfeng Li , Jiewen Zhou , Guangqing Liu , Gang Shu*, Zongyan Chen*.Hypericin-loaded graphene oxide protects ducks against a novel duck reovirus. Materials Science & Engineering C,2019(105):1-8.

(4). Rong Xiao, Xiaoyun Mi, Jiahui Sun, Mingyang Ding, Chuanfeng Li, Jie Zhu, Guangqing Liu, Wenge Ma, Hailong Zhou , Zongyan Chen*. Interaction between Translocation-associated membrane protein 1 and σC protein of novel duck reovirus controls virus infectivity. Virus Genes, 2020, 56:347-353.

(5). Xiaxia DU, Mingyang Ding, Qiaomei Wu, Chuanfeng Li, Huimin Guo, Guangqing Liu, Zongyan Chen*. Characterization of a P18 Protein in the S1 Segment of the Novel Duck Reovirus Genome. Acta Virol,2020, 64(1),59-66.

(6). Cong Huang, Yuanling Huang, Zhiyi Liu, Jia Li, Jingyi Han, Yingnan Liu, Jingyi Liu, Hongjun Chen, Zongyan Chen*.Isolation and characterization of a duck reovirus strain from mature ducks in China.Poult Sci, 2023 ;102(2):102345.

(7). Yuanling Huang , Gang Shu, Cong Huang, Jingyi Han, Jia Li, Hongjun Chen, Zongyan Chen*. Characterization and pathogenicity of a novel variant infectious bursal disease virus in China.Front Microbiol, 2023,17;13:1039259.

(8). Xinjin Shi, Xinyu Zhang, Haiwei Sun, Changqing Wei, Yingnan Liu, Jiguan Luo, Xuebo Wang ,Zongyan Chen* , Hongjun Chen. Isolation and pathogenic characterization of duck adenovirus 3 mutant circulating in China.Poult Sci, 2022 Jan;101(1):101564.

(9). Zongyan Chen, Yingqi Zhu, Guangqing Liu. Outbreak associated Novel Duck Reovirus,China,2011.Emerging Infectious Diseases, 2012,18(7):1210-1213.

(10). Zongyan Chen, Chuanfeng Li,Yingqi Zhu,et al. Immunogenicity of virus-like particles containing modified goose parvovirus VP2 protein. Virus Research, 2012,169(1): 306-309.

(11). Zongyan Chen, Chuanfeng Li, Gaojing Peng, et al. Expression, purification, characterization and subcellular localization of the goose parvovirus Rep1 protein. Protein and Peptide Letter,2013,20(7):820-5.

(12). Zongyan Chen,Chuanfeng Li, Guoxin Li,et al. Rapid Diagnosis of Goose Viral Infections by Multiplex PCR. Journal of virological methods,2013, 191(2):101-4.

(13). Zongyan Chen, Anchun Cheng, Mingwhu Wang, Dawei Xu, Wen Zeng, Zhan Li. Antiviral effects of PNA in duck hepatitis B virus infection model.Acta Pharmacol Sin. 2007,28(10):1652-8.

(14). Zongyan Chen, Anchun Cheng, Mingshu Wang, Dawei Xu, Renyong Jia, Yufei Guo, Weng Zeng.Viral load in 1-day-old ducklings acutely infected with duck hepatitis B virus by different doses and routes of inoculation. Avian Pathol. 2009 Apr;38(2):129-34.