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Introduction

Yingchun LIU

Positional title: Associate researcher

Education: PhD

Supervisor Category: Master Supervisor

Research Fields: Research and development of new antibacterial drugs, Residue depletion and risk assessment of veterinary drugs in food animals, and Metabolism of drugs in animals

1. Introdction

Yingchun Liu, Ph.D., Associate researcher, Master instructor. She has long been engaged in research and development of new antimicrobial agents, pharmacokinetics, veterinary drug residues and drug metabolism in animals, and has participated in the acquisition of two Class I New Veterinary Drug Certificates. She presided over four special fund projects for basic scientific research business expenses of public welfare scientific research institutes at the central level, presided over two projects of the National Natural Science Foundation of China, and trained seven postgraduate students. She has published more than 20 papers at home and abroad, such as “Journal of Agricultural and Food Chemistry”, “Veterinary Parasitology”, “Food Analytical Method”, “Journal of chromatography B”, etc., including 13 SCI papers and 5 patents.

2. Contact Information

Tel:021-34293396

Email:liuyingchun@shvri.ac.cn

3. Selected Publications

[1]. Wei Zhang, Jinxin Ran, Lu Shang, Lifang Zhang, Mi Wang, Chenzhong Fei, Chan Chen, Feng Gu, Yingchun Liu*. Niclosamide as a repurposing drug against gram-positive bacterial infections, Journal of Antimicrobial Chemotherapy, 2022, 77(12): 3312-3320.

[2]. Hao Zhang, Fayu Yang, Man Yang, Jing Liu, Mi Wang, Chenzhong Fei, Lifang Zhang, Feiqun Xue, Chuangang Zhu, Yingchun Liu*, Feng Gu*. An ultrasensitive, rapid, and portable method for screening oseltamivir-resistant virus based on CRISPR/Cas12a combined with immunochromatographic strips, Acta Biochmica et biophysica sinica, 2022, 54(11): 1630-1636.

[3]. Lu Shang, Chan Chen, Rui Sun, Juan Guo, Jing Liu, Mi Wang, Lifang Zhang, Chenzhong Fei, Feiqun Xue, Yingchun Liu*, Feng Gu*. Engineered Peptides Harboring Cation Motifs Against Multidrug Resistant Bacteria, ACS Applied Materials & Interfaces, 2024, 16(5): 5522-5535.

[4]. Yikai Fu, Junwen Zhou, Lifang Zhang, Chenzhong Fei , Xiaoyang Wang, Mi Wang, Chunmei Wang, Keyu Zhang, Feiqun Xue, Yingchun Liu*. Pharmacokinetics and anticoccidial activity of ethanamizuril in broiler chickens. Veterinary Parasitology. 2021,1(289):109318.

[5]. Yingchun Liu, Xiao Zhao, Chunmei Wang, Lifang Zhang, Keyu Zhang, Chenzhong Fei, Mi Wang, Feng Gu, Xiaoyang Wang, Yanxuan Li, Feiqun Xue. Metabolism, Distribution, and Excretion of Ethanamizuril in Chickens. Journal of Agricultural and Food Chemistry. 2020,6(68):1563-1570.

[6]. Yingchun Liu, Xiao Zhao, Chunmei Wang, Keyu Zhang, Lifang Zhang, Mi Wang, Chenzhong Fei, Xiaoyang Wang, Feiqun Xue. Simultaneously Quantification of Ethanamizuril Marker Residue in Edible Tissues of Chicken by Ultra- high Performance Liquid Chromatography- mass Spectrometry. Food Analytical Methods.2020,2(13):465-473.

[7]. Xiao Zhao, Youfa Xu, Lifang Zhang, Chunmei Wang, Chunna Guo, Chenzhong Fei, Keyu Zhang, Xiaoyang Wang, Yingchun Liu*, Mi Wang, Wenli Zheng, Feiqun Xue*. Development and validation of an UPLC-UV method for determination of a novel triazine coccidiostat ethanamizuril and its metabolite M3 in chicken tissues. Journal of Chromatography B. 2017,1059:1-6.

[8]. Yingchun Liu, Wei Jiang, Yongjun Chen, Yanyan Liu , Peng Zeng, Feiqun Xue, Quan Wang*. Cytotoxicity of mequindox and its metabolites in HepG2 cells in vitro and murine hepatocytes in vivo. Mutation Research/Genetic Toxicology and Environmental  Mutagenesis, 2016,2(797): 36-45. 10.1016/j.mrgentox.2016.01.002.  

[9]. Ying-Chun Liu, Wei Jiang, Yongjun Chen, Meng Zhang, Quan Wang*. Simultaneous detection of four nitrofuran metabolites in honey using high-throughput suspension array technology. Anal. Methods, 2015, 7,4097.  

[10]. Ying-Chun Liu, Quan Wang*, Wei Jiang, Yong-Jun Chen, Xinyu Zhao, Zhenyu Jing, Meng Zhang. Simultaneous determination of malachite green, diethylstilbestrol, medroxyprogesterone, and 3-amino-2-oxazolidone in synbranchoid eels by a protein microarray method. Food Anal. Methods.2015,4:1058-1066.  

4. Patents

[1]. A niclosamide injection and its preparation and application, 202111193757.3.

[2]. A single-chain antibody against influenza virus and its preparation method and application,ZL2012100638704.

[3]. A method for detecting acute infection of Toxoplasma gondii and its target protein,ZL2015102718162.

[4]. An efficient method for detecting acute infection of Toxoplasma gondii and its target protein,ZL2015102721875.

5. Awards

[1]. Ethanamizuril, ( 2020 ) Certificate of New Veterinary Drug Category I, No. 56.

[2]. Ethanamizuril solution, ( 2020 ) Certificate of New Veterinary Drug Category I, No. 57.