一、个人简历

邱亚峰，博士，研究员，博士生导师，团队执行首席。中国农业科学院青年英才入选者。长期从事病原微生物感染与免疫的基础研究，集中研究猪呼吸道传染病及人畜共患性传染病的免疫致病机制。主持国家级和省部级项目课题7项，培养博士生3名、硕士生12名、博士后1名。在《Journal of Immunology》《Developmental & Comparative Immunology》《Archives of Virology》等国内外杂志上发表论文100余篇，其中SCI论文80余篇。

二、联系方式

办公电话：021-34680292

邮      箱：yafengq@shvri.ac.cn

三、代表论著

1, Chen, X.J#., Shi, H.Y#., Cheng, X.Y., Wang, X.X., Li, Z.J., Shao, D.H., Liu, K., Wei, J.C., Li, B.B., Wang, J., Zhou, B., Ma, Z.Y.*, and Qiu, Y.F.* (2022) Expression Analysis of Outer Membrane Protein HPS_06257 in Different Strains of Glaesserella parasuis and Its Potential Role in Protective Immune Response against HPS_06257-Expressing Strains via Antibody-Dependent Phagocytosis.  Veterinary Sciences , 9(7), 342. doi: 10.3390/vetsci9070342

2, Zhang, Y.B., Xiang, X., Lu, Y., Li, H., Wahaab, A., Sharma, M., Liu, K., Wei, J.C., Li, Z.J., Shao, D.H., Li, B.B., Ma, Z.Y.*, and Qiu, Y.F.* (2021) Downregulation of miR-296-3p by highly pathogenic porcine reproductive and respiratory syndrome virus activates the IRF1/TNF-α signaling axis in porcine alveolar macrophages.  Archives of Virology , 166(2): 511-519. doi: 10.1007/s00705-020-04921-y

3, Xiang, X.#, Zhang, Y.B.#, Li, Q.Q., Wei, J.C., Liu, K., Shao, D.H., Li, B.B., Olszewski, M.A., Ma, Z.Y.*, and Qiu, Y.F.* (2020). Expression profile of porcine scavenger receptor A and its role in bacterial phagocytosis by macrophages.  Developmental & Comparative Immunology  104: 103534.

4, Lu, Y.#, Zhang, Y.B.#, Xiang, X., Sharma, M, Liu, K., Wei, J.C., Shao, D.H., Li, B.B., Tong, G.Z., Olszewski, M.A., Ma, Z.Y.*, and Qiu, Y.F.* (2020). Notch signaling contributes to the expression of inflammatory cytokines induced by highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection in porcine alveolar macrophages.  Developmental & Comparative Immunology  108: 103690.

5, Zhang, Y.B., Li, H., Xiang, X., Lu, Y., Sharma, M., Li, Z.J., Liu, K., Wei, J.C., Shao, D.H., Li, B.B., Ma, Z.Y., and Qiu, Y.F.* (2020). Identification of DNMT3B2 as the Predominant Isoform of DNMT3B in Porcine Alveolar Macrophages and Its Involvement in LPS-Stimulated TNF-a Expression.  Genes  11 (9): E1065. doi: 10.3390/genes11091065.

6, Huang, H.#, Sharma, M.#, Zhang, Y.B., Li, C.X., Liu, K., Wei, J.C., Shao, D.H., Li, B.B., Ma, Z.Y., Cao, R.B.*, and Qiu, Y.F.* (2020). Expression Profile of Porcine TRIM26 and Its Inhibitory Effect on Interferon-β Production and Antiviral Response.  Genes  11(10): E1226. doi: 10.3390/genes11101226.

7, Wang, Z.T.#, Zhang, Y.B.#, Wang, L.Y.#, Wei, J.C., Liu, K., Shao, D.H., Li, B.B., Liu, L.H., Widén, F., Ma, Z.Y.*, and Qiu, Y.F.* (2020). Comparative genomic analysis of Bordetella bronchiseptica isolates from the lungs of pigs with porcine respiratory disease complex (PRDC).  Infection, Genetics and Evolution  81: 104258.

8, Shi, Y.Y.#*, Jiang, W.#, Ma, Z.Y., and Qiu, Y.F.* (2017). A case report of pulmonary tritrichomonosis in a pig.  BMC Veterinary Research  13(1): 348.

9, Li, Y.M., Wu, Z.C., Liu, K., Qi, P.F., Xu, J.P., Wei, J.C., Li, B.B., Shao, D.H., Shi, Y.Y., Qiu, Y.F.*, and Ma, Z.Y.* (2017). Proteomic Analysis of the Secretome of Porcine Alveolar Macrophages Infected with Porcine Reproductive and Respiratory Syndrome Virus.  Proteomics  17(21): doi: 10.1002/pmic.201700080.

10, Qi, P.F.#, Liu, K.#, Wei, J.C., Li, Y.M., Li, B.B., Shao, D.H., Wu, Z.C., Shi, Y.Y., Tong, G.Z., Qiu, Y.F.*, and Ma, Z.Y.* (2017). Nonstructural Protein 4 of Porcine Reproductive and Respiratory Syndrome Virus Modulates Cell Surface Swine Leukocyte Antigen Class I Expression by Downregulating β2-Microglobulin Transcription. Journal of  Virology  91(5): e01755-16.

四、发明专利

1. 一类N-(2-噻唑)苯甲酰胺衍生物的应用，中国，ZL201010237252.8

2. 一种重组抗病毒蛋白及其制备方法和应用，中国，ZL201610340303.7

3. IRAK-M多克隆抗体及其制备方法，中国，CN2017108284467

4. 一种DNA甲基化转移酶1的抗原肽及其多克隆抗体，中国，CN202111661755.2

5. 一种用于防控猪呼吸道传染病的沙克乳酸杆菌及其应用, 中国, CN202110020751.X

6. 一种非洲猪瘟病毒LAMP-LFD可视化检测方法、试剂盒及其使用方法,中国，CN202011105829.X