一、个人简历

孔宁，博士，副研究员，硕士生导师，猪病毒性繁殖障碍疫病防控技术研究团队科研助理。

长期从事猪流行性腹泻病毒致病性与宿主免疫机制方向的研究。主持国家自然科学基金青年基金项目1项，中国农业科学院青年创新专项任务1项，上海市自然科学基金1项，中国博士后科学基金1项。在《Autophagy》《Journal of Virology》《Microbiology Spectrum》等国内外发表论文40余篇，其中SCI论文26篇，获专利1项。

二、联系方式

办公电话：021-34293773

邮      箱：kongning@shvri.ac.cn

三、代表论著

1. Ning Kong^#, Tongling Shan^#, Hua Wang, Yajuan Jiao, Yewen Zuo, Liwei Li, Wu Tong, Lingxue Yu, Yifeng Jiang, Yanjun Zhou, Guoxin Li, Fei Gao, Hai Yu, Hao Zheng, Guangzhi Tong. BST2 suppresses porcine epidemic diarrhea virus replication by targeting and degrading virus nucleocapsid protein with selective autophagy. Autophagy 2020; 16:1737-52. IF="16.016

2. Dage Sun^#, Ning Kong^#, Sujie Dong^#, Xiaoyong Chen, Wenzhen Qin, Hua Wang, Yajuan Jiao, Huanjie Zhai, Liwei Li, Fei Gao, Lingxue Yu, Hao Zheng, Wu Tong, Hai Yu, Wen Zhang, Guangzhi Tong, Tongling Shan. 2AB protein of Senecavirus A antagonizes selective autophagy and type I interferon production by degrading LC3 and MARCHF8. Autophagy 2021. IF="13.391

3. Yajuan Jiao^#, Ning Kong^#, Hua Wang^#, Dage Sun^#, Sujie Dong, Xiaoyong Chen, Hao Zheng, Wu Tong, Hai Yu, Lingxue Yu, Yaowei Huang, Huan Wang, Baokun Sui, Ling Zhao, Ying Liao, Wen Zhang, Guangzhi Tong, Tongling Shan. PABPC4 broadly inhibits coronavirus replication by degrading nucleocapsid protein through selective autophagy. Microbiology Spectrum, 2021, 9:e00908-21. IF="9.043

4. Hua Wang^#, Ning Kong^#, Yajuan Jiao^#, Sujie Dong^#, Dage Sun, Xiaoyong Chen, Hao Zheng, Wu Tong, Hai Yu, Lingxue Yu, Wen Zhang, Guangzhi Tong, Tongling Shan. EGR1 suppresses porcine epidemic diarrhea virus replication by regulating IRAV to degrade viral nucleocapsid protein. Journal of Virology, 2021, 95:e00645-21. IF="6.549

5. Sujie Dong#, Ning Kong#, Yu Zhang#, Youwen Li#, Dage Sun, Wenzhen Qin, Huanjie Zhai, Xueying Zhai, Xinyu Yang, Chenqian Ye, Manqing Ye, Changlong Liu, Lingxue Yu, Hao Zheng, Wu Tong, Hai Yu, Wen Zhang, Guangzhi Tong*, Tongling Shan*. TARDBP inhibits porcine epidemic diarrhea virus replication by degrading viral nucleocapsid protein and activating type I IFN signaling. Journal of Virology. 2022. IF="6.549

6. Sujie Dong#, Ning Kong#, Chunmei Wang#, Youwen Li, Dage Sun, Wenzhen Qin, Huanjie Zhai, Xueying Zhai, Xinyu Yang, Chenqian Ye, Manqing Ye, Changlong Liu, Lingxue Yu, Hao Zheng, Wu Tong, Hai Yu, Wen Zhang, Guangzhi Tong*, Tongling Shan*. FUBP3 degrades the PEDV nucleocapsid protein and induces the production of type I interferon. Journal of Virology. 2022. IF="6.549

7. Wenzhen Qin#, Ning Kong#, Yu Zhang#, Sujie Dong, Huanjie Zhai, Xueying Zhai, Xinyu Yang, Chenqian Ye, Manqing Ye, Changlong Liu, Lingxue Yu, Hao Zheng, Hai Yu, Wen Zhang, Guangzhi Tong, Daoliang Lan*, Wu Tong*, Tongling Shan*. Nuclear ribonucleoprotein RALY targets virus nucleocapsid protein and induces autophagy to restrict porcine epidemic diarrhea virus replication. Journal of Biological Chemistry. 2022. IF="5.486

8. Kong Ning^#, Meng Qiong^#, Jiao Yajuan^#, Wu Yongguang, Zuo Yewen, Wang Hua, Sun Dage, Dong Sujie, Zhai Huanjie, Tong Wu, Zheng Hao, Yu Hai, Tong Guangzhi, Xu Yongjie*, Shan Tongling*. Identification of a novel B-cell epitope in the spike protein of porcine epidemic diarrhea virus. Virology Journal, 2020, 17(1): 0-46. IF="4.099

四、专利标准

【抗猪流行性腹泻病毒N蛋白的单克隆抗体及其应用】，授权公告日：2019年03月29日，国家发明专利，专利号：ZL201410384478.9