一、个人简历

蒋蔚，博士，研究员，博士生导师。长期从事副溶血弧菌、副鸡嗜血杆菌和产气荚膜梭菌等病原微生物的致病机制，以及布鲁氏菌病、奶牛乳腺炎和重要食源性疾病的新型诊断检测技术研究。获上海市科学进步奖、中国检验检疫学会科技奖、上海市浦东新区科学进步奖、中华人民共和国上海海关科技兴检奖等6项奖项。主持国家自然基金面上项目、国家自然科学基金联合基金项目课题、国家重点研发计划项目子课题、上海市自然基金面上项目、上海市科学委员会创新计划项目等20余项，培养（含联合培养）硕士和博士研究生共20余名。以第一或通讯作者论文在《Biosensors and Bioelectronics》《Chemical Engineering Journal》《Food Control》等国内外杂志上发表论文50余篇，出版专著1部，获专利8项，科技成果认证3项，形成行业标准2项。

二、联系方式

办公电话：021-34293397

邮      箱：jiangwei@shvri.ac.cn

三、代表论著

[1] Jiayuan Zheng, Jinhua Li, Tianci Lin , Zhanpeng Ren, Fucheng Wang, Zhonghao Shi , Haiyang Yu, Wei Jiang , Wei Tang, Ampliffcation-free and label-free rapid detection of Staphylococcus aureus using solution-gated graphene transistor-based DNA biosensor with hybridization enhancement by interface engineering. Chemical Engineering Journal 495 (2024) 153329

[2] Fucheng Wang, Fangyu Yea, Wei Tang, Quan Wang, Chenye You, Haiyang Yu, Xin Zhou, Xiangan Han, Wei Jiang. Triplex immunomagnetic separation combined with loop-mediated isothermal amplification on a microfluidic chip for simultaneous visual detection of Escherichia coli O157:H7, Salmonella enteritidis and Staphylococcus aureus in milk. Food Control. 2024 (165):110629.

[3] Wenchao Wang, Yangyang Li, Shuqi Lu, Pengxuan Liu, Xiangan Han, Weidong Sun, Quan Wang, Weihuan Fang and Wei Jiang. BolA-like protein (IbaG) promotes biofilm formation and pathogenicity of Vibrio parahaemolyticus. Frontiers in Microbiology. 

[4] Pengxuan Liu, Xiaoyun Zhang, Quan Wang, Yang-yang Li,, Weidong Sun, Yu Qi, Kai Zhou, Xiangan Han, Zhaoguo Chen, Weihuan Fang, Wei Jiang. Biological and transcriptional studies reveal VmeL is involved in motility, biofilm formation and virulence in Vibrio parahaemolyticus. Frontiers in Microbiology. 13:976334.

[5] Haiyang Zhang, Quan Wang, Haoxiang Zhuang, Qiu Lin, Wenchao Wang, Fangyu Ye,Saqib Nawaz1, Jiangang Hu, Cuiqin Huang, Huifang Yin, Weidong Sun, Xiangan Han, and Wei Jiang. Development of Recombinant Antibodies and Its Application in Immunomagnetic Separation-Based Rapid Detection of Vibrio cholerae in Aquatic Environments. Journal of microbiolodgy and biotechnology. 2024.34(11):1-13

[6] Xue-rui Bai, Peng-xuan Liu, Wen-chao Wang，Yinghong Jin, Quan Wang, Yu Qi, Xiao-yun Zhang, Wei-huan Fang, Xian-gan Han,Wei Jiang.TssL2 of T6SS2 is required for mobility, biofilm formation, wrinkly phenotype formation, and virulence of Vibrio parahaemolyticus SH112. Applied Microbiology and Biotechnology,2024.10.1007/s00253-024-13351-8

[7] Yangyang Li , Weidong Sun , Quan Wang, Ying Yu, Ying Wan, Kai Zhou, Rong Guo ,Xiangan Han, Zhaoguo Chen , Weihuan Fang , Wei Jiang. The GntR-like transcriptional regulator HutC involved in motility, biofilm-forming ability, and virulence in  Vibrio parahaemolyticus . Microbial Pathogenesis, 2022, 167: 105546

[8] Wei Jiang, Yingchun Liu, Yongjun Chen, Peter Chun, Kailing Yao, Xiangan Han, Shaohui Wang, Shengqing Yu, Yongjie Liu, Quan Wang. A novel dynamic flow immunochromatographic test (DFICT) using gold nanoparticles for the serological detection of  Toxoplasma gondii  infection in dogs and cats. Biosensors and Bioelectronics, 2015, 72: 133–139.

[9] Wei Jiang, Yaling Ren, Xiangan Han, Tongling Shan, Junxin Xue, Zhaoguo Chen, Yongjie Liu, Quan Wang. Recombinase polymerase amplification-lateral flow (RPA-LF) assay combined with immunomagnetic separation for rapid visual detection of  Vibrio parahaemolyticus  in raw oysters. Analytical and Bioanalytical Chemistry, 2020, 412(12): 2903-2914.

[10] Quan Wang, Mengyao Long, Caiyun Lv, Sipei Xin, Xiangan Han, Wei Jiang. Lanthanide-labeled fluorescent-nanoparticle immunochromatographic strips enable rapid and quantitative detection of  Escherichia coli  O157:H7 in food samples. Food Control, 2020, 109: 106894.  

[11] Yun Chen, Qi Liu, Jun-Xin Xue, Man-Yu Zhang, Xiao-Ling Geng, Quan Wang and Wei Jiang. Genome-wide CRISPR/Cas9 screen identifies new genes critical for defense against oxidant stress in  Toxoplasma gondii.  Frontiers in Microbiology, 2021, 12: 670705.

四、专利标准

[1] 一种用于检测副溶血弧菌的试剂盒、引物对、探针和方法. 授权公告日：2020.06.19，中国，ZL201910281743.3.

[2] 抗金黄色葡萄球菌单克隆抗体、应用及包含其的免疫磁珠. 授权公告日：2022.03.03，中国，ZL20211072909.8.

[3] 一种检测弓形虫急性感染的方法及其靶标蛋白. 授权公告日：2017.02.08，中国，ZL201510271816.2.

[4] 一种抗流感病毒的单链抗体及其制备方法和应用. 授权公告日：2014.06.04，中国，ZL201210063870.4.

[5] 一种高效检测弓形虫急性感染的方法及其靶标蛋白. 授权公告日：2017.06.27，中国，ZL20151 0272187.5.

[6] 禽致病性大肠杆菌等的多重PCR检测引物组、方法及试剂盒. 授权公告日：2021.07.16，中国，ZL201810317451.6.

[7] 一种利用含双特异性抗体的胶体金试纸条检测细菌的方法,专 利 号：ZL 2020 1 1146123.8，授 权 公 告 日：2023年10月13日

[8] 水生动物副溶血弧菌和霍乱弧菌双重实时荧光检测方法. 出入境检验检疫行业标准SN/T5125-2019.

五、奖励成果

[1] 上海市科学进步奖三等奖，动物疫病和动物源性食品安全防控检测中新技术的开发与应用，证书编号：20174200-3-R02.

[2] 上海出入境检验检疫局科技兴检奖三等奖，弓形虫病快速检测方法的研究与应用，证书编号：2017-028-3-R02.

[3] 2023年闵行区职工科技创新成果三等奖“动物疫病和动物源性食品安全防控检测中新技术的开发与应用”