一、个人简历

陈宗艳，博士，研究员，博士/硕士生导师。长期从事动物传染病病原及生物制品研制。主持国家及省部级课题 10 余项，包括国家自然科学基金、上海市自然科学基金、上海市科委-创新行动计划、中央级公益性科研院所基本科研业务费、十三五国家重点研发计划子课题、十四五国家重点研发计划子课题等；主持横向开发与成果转化10余项；培养（含联合培养）硕博士研究生15名。在Cell Reports,Plos Biology,Emerging infectious diseases,Journal of General Virology,等国内外发表论文60余篇，其中SCI论文30篇，出版专（译）著2部，申请获得疫苗或抗体临床批件4项。

二、联系方式

办公电话：021-34293155 54082828

邮      箱：zychen@shvri.ac.cn

三、代表论著

[1] Chenxu Feng, Ge Wang, Yixuan Wang, Xiang Gao, Zhenqi Xu, Luyao Fang, Ziyi Ma, Suwei Zheng, Yuyan Xie, Yufeng Chu, Mei Meng, Angela Yang, Miriam Lu, Judd Denzel Garcia Mondina, Weiwei Zhu, Lisheng Zhang, Linqi Wang, 
Zongyan Chen*, Donglei Sun, Microglia sense fungal infections through capsular components from capillary-bound Cryptococcus neoformans via endothelial nucleotide signaling, Plos Biology, 2026, 24(2)

[2] Wang Ge, Feng, Chenxu, Ma Ziyi, Zhao Lu, Yosri Mohammed, WangYixuan, Gao Xiang, Zhu Weiwei, Li Hongmei, SongHaihan, Xia Jianhua, Meng Mei, 
Lu Hongzhong, Zhang Lisheng, Zongyan Chen*, Sun Donglei*, In toto imaging shows intravascular proliferation promotes transmigration of daughter cells during brain invasion of Cryptococcus neoformans, Cell Reports, 2025, 44(12)

[3] Gang Shu，Jingyi Han，Yuanling Huang，Cong Huang，Liping Kong，Hongchang Li，Lu Zhao，Qijiang Tang，Jia Li，Yingnan Liu，Jingyi Liu，Hongjun Chen，Zongyan Chen. Adjuvanting a subunit novel variant IBDV vaccine to induce protective immunity.Journal of Integrative Agriculture.2025, 24(5): 2019-2023

[4] Xinjin Shi, Xinyu Zhang, Haiwei Sun, Changqing Wei, Yingnan Liu, Jiguan Luo, Xuebo Wang, Zongyan Chen*, Hongjun Chen. Isolation and pathogenic characterization of duck adenovirus 3 mutant circulating in China, Poult Sci.2022,101(1):101564.

[5] Cong Huang, Yuanling Huang, Zhiyi Liu, Jia Li, Jingyi Han, Yingnan Liu, Jingyi Liu, Hongjun Chen, Zongyan Chen*.Isolation and characterization of a duck reovirus strain from mature ducks in China.Poult Sci, 2023 ;102(2):102345.

[6] Yuanling Huang , Gang Shu, Cong Huang, Jingyi Han, Jia Li, Hongjun Chen, Zongyan Chen*. Characterization and pathogenicity of a novel variant infectious bursal disease virus in China.Front Microbiol, 2023,17;13:1039259.

[7] Rong Xiao, Xiaoyun Mi, Jiahui Sun, Mingyang Ding, Chuanfeng Li, Jie Zhu, Guangqing Liu, Wenge Ma, Hailong Zhou* , Zongyan Chen*. Interaction between Translocation-associated membrane protein 1 and σC protein of novel duck reovirus controls virus infectivity. Virus Genes, 2020, 56:347-353.

[8] Xinjin Shi, Xinyu Zhang, Haiwei Sun, Changqing Wei, Yingnan Liu, Jiguan Luo, Xuebo Wang ,Zongyan Chen* , Hongjun Chen. Isolation and pathogenic characterization of duck adenovirus 3 mutant circulating in China.Poult Sci, 2022 Jan;101(1):101564.

[9] Wu Qiaomei, Ding Mingyang, Li Chuanfeng, Liu Guangqing, Chen Zongyan*. Construction and characterization of an infectious molecular clone of novel duck reovirus.  Journal of General Virology,2018 ;99(4) 449–4561.

[10] Xiaxia Du, Rong Xiao, Hualin Fu , Zhixiang Yuan , Wei Zhang , Lizi Yin , Changliang He , Chuanfeng Li , Jiewen Zhou , Guangqing Liu , Gang Shu*, Zongyan Chen*.Hypericin-loaded graphene oxide protects ducks against a novel duck reovirus. Materials Science & Engineering C,2019(105):1-8.

[11] 参编《动物反向遗传学》，科学出版社，2014年。

四、专利标准

1. 一种鸭呼肠孤病毒oC蛋白单克隆抗体及其杂交瘤细胞株和应用, 2025.09.02，中国，ZL 202410887447.9

2. RK-13细胞HBB基因敲除稳定株的构建方法，2020.12.08，中国，ZL201710200878.3

3. 兔病毒性出血症病毒突变株及其构建方法、用途，2018.08.14，中国，ZL201510044194.X。

4. 一种鸭的TLR3基因的荧光定量PCR检测方法，2017.01.11，中国，ZL201510067874.3。

五、奖励成果

1.兽用生物制品临床试验批件4项，第一完成人2项，第二完成人2项。

2.“转化英才”荣誉称号。