一、个人简历

鲍衍清，男，博士，所聘研究员，中国农业科学院优秀青年英才，畜禽细菌性传染病风险预警与防控创新团队骨干专家。2017年10月-2021年12月，美国德克萨斯大学艾尔帕索分校博士后。2022年1月至今，在中国农业科学院上海兽医研究所工作，从事人兽共患型胞内寄生菌的基础和应用研究，主要开展布鲁氏菌和分枝杆菌的胞内存活基因、致病机制、检测试剂盒和人工智能监测技术研究。发表多篇SCI收录文章，获得授权国家发明专利2件。

二、联系方式

办公电话：021- 34293412

邮      箱：ybao@shvri.ac.cn

三、代表论著

1. Zuo, W.; Yang, D.; Wu, X.; Zhang, B.; Wang, X.; Hu, J.; Qi, J.; Tian, M.; Bao, Y.; Wang, S. The aroA and luxS Double-Gene Mutant Strain Has Potential to Be a Live Attenuated Vaccine against Salmonella Typhimurium. Vaccines (Basel) 2024, 12 (2). DOI: 10.3390/vaccines12020162.

2. Zuo, W.; Tian, M.; Qi, J.; Zhang, G.; Hu, J.; Wang, S.; Bao, Y. The functions of EF-hand proteins from host and zoonotic pathogens. Microbes Infect 2023, 105276. DOI: 10.1016/j.micinf.2023.105276.

3. Bao Y, Wang L, Sun J. A Small Protein but with Diverse Roles: A Review of EsxA in Mycobacterium-Host Interaction. Cells. 2021;10(7).

4. Bao Y, Wang L, Sun J. Post-translational knockdown and post-secretional modification of EsxA determine contribution of EsxA membrane permeabilizing activity for mycobacterial intracellular survival. Virulence. 2021;12(1):312-28.

5. Zuo X, Wang L, Bao Y, Sun J. The ESX-1 Virulence Factors Downregulate miR-147-3p in Mycobacterium marinum-Infected Macrophages. Infect Immun. 2020;88(6).

6. Bao Y, Zhao X, Wang L, Qian W, Sun J. Morphology-based classification of mycobacteria-infected macrophages with convolutional neural network: reveal EsxA-induced morphologic changes indistinguishable by naked eyes. Transl Res. 2019;212:1-13.

7. Wu H, Bao Y, Wang L, Li X, Sun J. Mycobacterium marinum down-regulates miR-148a in macrophages in an EsxA-dependent manner. Int Immunopharmacol. 2019;73:41-8.

8. Tian M, Bao Y, Li P, Hu H, Ding C, Wang S, et al. The putative amino acid ABC transporter substrate-binding protein AapJ2 is necessary for Brucella virulence at the early stage of infection in a mouse model. Vet Res. 2018;49(1):32.

9. Bao Y, Tian M, Li P, Liu J, Ding C, Yu S. Characterization of Brucella abortus mutant strain Δ22915, a potential vaccine candidate. Vet Res. 2017;48(1):17.

10. Gao J, Tian M, Bao Y, Li P, Liu J, Ding C, et al. Pyruvate kinase is necessary for Brucella abortus full virulence in BALB/c mouse. Vet Res. 2016;47(1):87.

11. Tian M, Qu J, Bao Y, Gao J, Liu J, Wang S, et al. Construction of pTM series plasmids for gene expression in Brucella species. J Microbiol Methods. 2016;123:18-23.

12. Miao J, Bao Y, Ye J, Shao H, Qian K, Qin A. Transcriptional Profiling of Host Gene Expression in Chicken Embryo Fibroblasts Infected with Reticuloendotheliosis Virus Strain HA1101. PLoS One. 2015;10(5):e0126992.