一、个人简历

李蓓蓓，农学博士，研究员，博士生导师，新疆农业大学兼职博士生导师。上海市青年科技启明星，中国农业科学院青年英才培育工程所级入选者。长期从事动物源细菌耐药性流行病学、新耐药机制解析、重要耐药基因的传播分子机理以及耐药快速检测技术的开发应用研究。主持国家和省部级各类项目7项，培养（含联合培养）博士生1名、硕士生6名。在《Journal of Antimicrobial Chemotherapy》《Plos Pathogens》《Veterinary Microbiology》等国内外发表论文30余篇，其中SCI论文25篇，出版专（译）著1部，获专利4项。

二、联系方式

办公电话：021-34510616

邮      箱：lbb@shvri.ac.cn

三、代表论著

1. Xin Wang, Zhuanchang Wu, Yuming Li, Yifan Yang, Changguang Xiao, Xiqian Liu, Xiao Xiang, Jianchao Wei, Donghua Shao, Ke Liu, Xufang Deng, Jiaqiang Wu , Yafeng Qiu, Beibei Li^※, Zhiyong Ma^※. p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication. Plos pathogens 2020 16, e1009035, doi:10.1371/journal.ppat.1009035. (Corresponding author)

2. Huiyong Xuan, Xiaohui Yao, Ruyi Pan, Yun Gao, Jianchao Wei, Donghua Shao, Ke Liu, Zongjie Li, Yafeng Qiu, Zhiyong Ma, Beibei Li^※, Lining Xia^※. (2021). Antimicrobial resistance in Enterococcus faecium and Enterococcus faecalis isolates of swine origin from eighteen provinces in China. Journal of Veterinary Medical Science, advpub. doi: 10.1292/jvms.21-0413 (Corresponding author).

3. Yun Gao , Lining Xia , Ruyi Pan , Huiyong Xuan , Hongdou Guo , Qiangqiang Song , Jianchao Wei , Donghua Shao , Ke Liu , Zongjie Li , Yafeng Qiu , Zhiyong Ma^※, Beibei. Li^※. Identification of mcr-1 and a novel chloramphenicol resistance gene catT on an integrative and conjugative element in an Actinobacillus strain of swine origin. Veterinary Microbiology 2021 254, 108983. (Corresponding author)

4. Huixian Tong，Juxiang Liu，Xiaohui Yao，Haiyan Jia，Jianchao Wei， Donghua Shao， Ke Liu， Yafeng Qiu， Zhiyong Ma^※， Beibei Li^※ High carriage rate of mcr-1 and antimicrobial resistance profiles of mcr-1-positive Escherichia coli isolates in swine faecal samples collected from eighteen provinces in China. Veterinary microbiology 2018, 225, 53-57. (Corresponding author)

5. Jianchao Wei,  Xin Wang,  Junjie Zhang,  Shuang Guo,  Linlin Pang,  Kun Shi,  Ke Liu,  Donghua Shao,  Yafeng Qiu,  Lihong Liu,  Frederik Widén,  Beibei Li^※, Zhiyong Ma^※. Partial cross-protection between Japanese encephalitis virus genotype I and III in mice. PLoS neglected tropical diseases, 2019, 13(8): e0007601. (Corresponding author)

6. Li Chenxi, Di Di, Wang Xin, Xia Qiqi, Wahaab Abdul, Anwar Muhammad Naveed, Li Zongjie, Liu Ke, Shao Donghua, Qiu Yafeng， Beibei Li^※, Zhiyong Ma^※: Duck karyopherin α4 (duKPNA4) is involved in type I interferon expression and the antiviral response against Japanese encephalitis virus. Developmental & Comparative Immunology 2020, 104:103535. (Corresponding author)

7. Beili Huan, Ke Liu, Yuming Li, Jianchao Wei, Donghua Shao, Yuanyuan Shi, Yafeng Qiu, Beibei Li^※ and Zhiyong Ma^※. Porcine serum amyloid A3 is expressed in extrahepatic tissues and facilitates viral replication during porcine respiratory and reproductive syndrome virus infection. Developmental and comparative immunology. 2018;79:51-58. (Co-corresponding author)

8. Jinpeng Xu， Haiyan Jia， Guanghui Cui， Huixian Tong， Jianchao Wei， Donghua Shao， Ke Liu， Yafeng Qiu， Beibei Li^※ and ZhiyongMa^※. ICEAplChn1, a novel SXT/R391 integrative conjugative element (ICE), carrying multiple antibiotic resistance genes in Actinobacillus pleuropneumoniae, Veterinary Microbiology, 2018. 220:18-23. (Co-corresponding author)

9. Beibei Li, Jiannan Yao, Jinachao Wei, Donghua Shao, Ke Liu, Yafeng Qiu and Zhiyong Ma. Characterization of fluoroquinolone resistance in methicillin-resistant Staphylococcus aureus of human and pig origin. Journal of global antimicrobial resistance. 2018. 12: 77-78.

10. Beibei Li, Licai Ma, Yingli Li, Haiyan, Jia, Jianchao Wei, Donghua Shao, Ke Liu, Yuanyuan Shi, Yafeng Qiu and Zhiyong Ma. Antimicrobial Resistance of Campylobacter Species Isolated from Broilers in Live Bird Markets in Shanghai, China. Foodborne pathogens and disease. 2017. 14: 96-102

四、专利标准

1，一步法检测Z/S亚型埃博拉病毒的实时荧光定量RT-PCR方法及其试剂盒。国家发明专利，专利号：ZL201110312855。授权公告日：2017年03月22日。

2，一类抗乙脑病毒感染的组合物及其应用。国家发明专利，专利号：ZL201510391532。授权公告日：2018年10月23日。

3，抑制流感病毒相关基因的SiRNA及其应用。国家发明专利，专利号：ZL201610139670。授权公告日：2018年08月31日。

4，一种重组载体及其在制备或筛选抗流感药物中的应用。国家发明专利，专利号：ZL201610141142。授权公告日：2019年04月02日。