一、个人简历

闫大为，博士，副研究员，硕士生导师，长期从事禽病毒学方向研究，先后主持和参与国家和省部级项目、课题10余项，在《Journal of Virology》等国内外发表论文10余篇，获得新兽药证书2项（排名第五、第六），获得兽用生物制品临床批件1项（排名第二），获得上海春申金字塔杰出人才，中国农业科学院科技进步成果奖1项（排名第六）。

二、联系方式

办公电话：021-34293604

邮箱：yandawei@shvri.ac.cn

三、代表论著

1. Yan D, Shi Y, Wang H, Li G, Li X, Wang B, Su X, Wang J, Teng Q, Yang J, Chen H, Liu Q, Ma W, Li Z. A Single Mutation at Position 156 in the Envelope Protein of Tembusu Virus Is Responsible for Virus Tissue Tropism and Transmissibility in Ducks. J Virol. 2018 Aug 16;92(17):e00427-18.

2. 2Yan D#, Wang B#, Shi Y#, Ni X, Wu X, Li X, Liu X, Wang H, Su X, Teng Q, Yang J, Liu Q, Li Z. A Single Mutation at Position 120 in the Envelope Protein Attenuates Tembusu Virus in Ducks. Viruses. 2022 Feb 22;14(3):447.

3. Yan D, Li X, Wang Z, Liu X, Dong X, Fu R, Su X, Xu B, Teng Q, Yuan C, Zhang Z, Liu Q, Li Z. The emergence of a disease caused by a mosquito origin Cluster 3.2 Tembusu virus in chickens in China. Vet Microbiol. 2022 Sep;272:109500.

4. Liu X#, Yan D#, Peng S, Zhang Y, Xu B, Li L, Shi X, Ma T, Li X, Teng Q, Yuan C, Liu Q, Li Z. 326K at E Protein Is Critical for Mammalian Adaption of TMUV. Viruses. 2023 Dec 1;15(12):2376.

5. Teng Q, Shen W, Yan D, Yan L, Li X, Li G, Yang J, Li Z. Development of a TaqMan MGB RT-PCR for the rapid detection of H3 subtype avian influenza virus circulating in China. J Virol Methods. 2015 Jun 1;217:64-9.

6. Wu X, Shi Y, Yan D, Li X, Yan P, Gao X, Zhang Y, Yu L, Ren C, Li G, Yan L, Teng Q, Li Z. Development of a PCR-Based Reverse Genetics System for an Attenuated Duck Tembusu Virus Strain. PLoS One. 2016 Jun 1;11(6):e0156579.

7. Yang J, Huang M, Qiao S, Zhang P, Teng Q, Li X, Liu Q, Chen H, Zhang Z, Yan D, Li Z. Replication and virulence of chimeric bat influenza viruses in mammalian and avian cells and in mice. Microb Pathog. 2021 Aug;157:104992.

8. Yang J, Zhang P, Huang M, Qiao S, Liu Q, Chen H, Teng Q, Li X, Zhang Z, Yan D, Sun H, Li Z. Key Amino Acids of M1-41 and M2-27 Determine Growth and Pathogenicity of Chimeric H17 Bat Influenza Virus in Cells and in Mice. J Virol. 2021 Sep 9;95(19):e0101921.

9. Su X, Shuo D, Luo Y, Pan X, Yan D, Li X, Lin W, Huang D, Yang J, Yuan C, Liu Q, Teng Q, Li Z. An Emerging Duck Egg-Reducing Syndrome Caused by a Novel Picornavirus Containing Seven Putative 2A Peptides. Viruses. 2022 Apr 29;14(5):932.

10. Xu B#, Liu X#, Yan D, Teng Q, Yuan C, Zhang Z, Liu Q, Li Z. Generation and characterization of chimeric Tembusu viruses containing pre-membrane and envelope genes of Japanese encephalitis virus. Front Microbiol. 2023 Jun 22;14:1140141.

四、奖励成果

1. 获得1项新兽药证书（三类）：鸭坦布苏病毒病活疫苗（FX2010-180P株），证号:（2018）新兽药证字41号，排名第六；

2. 获得1项新兽药证书（一类）：鸭坦布苏病毒ELISA抗体检测试剂盒，证号（2021）新兽药证字45号，排名第五；

3. 获得2022年度上海春申金字塔杰出人才；

4. 获得2023年中国农业科学院科技进步成果奖，排名第六。