团队成员
闫大为
职称: 副研究员
学历: 博士研究生
导师类别: 硕士生导师
研究方向: 禽病毒学方向研究
一、个人简历
闫大为,博士,副研究员,硕士生导师,长期从事禽病毒学方向研究,先后主持和参与国家和省部级项目、课题10余项,在《Journal of Virology》等国内外发表论文10余篇,获得新兽药证书2项(排名第五、第六),获得兽用生物制品临床批件1项(排名第二),获得上海春申金字塔杰出人才,中国农业科学院科技进步成果奖1项(排名第六)。
二、联系方式
办公电话:021-34293604
邮箱:yandawei@shvri.ac.cn
三、代表论著
1. Yan D, Shi Y, Wang H, Li G, Li X, Wang B, Su X, Wang J, Teng Q, Yang J, Chen H, Liu Q, Ma W, Li Z. A Single Mutation at Position 156 in the Envelope Protein of Tembusu Virus Is Responsible for Virus Tissue Tropism and Transmissibility in Ducks. J Virol. 2018 Aug 16;92(17):e00427-18.
2. 2Yan D#, Wang B#, Shi Y#, Ni X, Wu X, Li X, Liu X, Wang H, Su X, Teng Q, Yang J, Liu Q, Li Z. A Single Mutation at Position 120 in the Envelope Protein Attenuates Tembusu Virus in Ducks. Viruses. 2022 Feb 22;14(3):447.
3. Yan D, Li X, Wang Z, Liu X, Dong X, Fu R, Su X, Xu B, Teng Q, Yuan C, Zhang Z, Liu Q, Li Z. The emergence of a disease caused by a mosquito origin Cluster 3.2 Tembusu virus in chickens in China. Vet Microbiol. 2022 Sep;272:109500.
4. Liu X#, Yan D#, Peng S, Zhang Y, Xu B, Li L, Shi X, Ma T, Li X, Teng Q, Yuan C, Liu Q, Li Z. 326K at E Protein Is Critical for Mammalian Adaption of TMUV. Viruses. 2023 Dec 1;15(12):2376.
5. Lu H, Tang M, Zhang Z, Wu M, Yuan C, Pan X, Liu Q, Teng Q, Xu B, Yan M, Yan D*, Wang F*, Li Z. The Isolation and Construction of an Infectious Clone for a Duck Adenovirus Type 3 Strain. Microorganisms. 2025, 13(6): 1319.
6. Tang M, Shi X, Xiong Y, Yuan C, Zhu Q, Huang M, Xu B, Liu Q, Pan X, Zhang Z, Teng Q, Yan M, Yan D*, Li Z*. Development of a Blocking ELISA for Detection of Serum Neutralizing Antibodies Against Duck Adenovirus Type 3. Microorganisms. 2025, 13(11): 2607.
7. Huang M, Shuo D, Xiong Y, Tang M, Wang Y, Pan X, Yuan C, Liu Q, Zhang Z, Teng Q, Xu B, Shi X, Yan M, Jiao P, Li Z*, Yan D*. Isolation and Characterization of a Duck Hepatitis A Virus Type 3 SH52 Strain in Ducklings. Microorganisms. 2025, 13(12): 2652.
8. Yuan S, Fu R, Xu B, Wang W, Ding H, Pan X, Yuan C, Liu Q, Zhang Z, Teng Q, Shi X, Yan M, Jiao P, Yan D*, Li Z*. Identification of novel B-cell neutralizing epitopes in goose Astrovirus type 2. Vet Microbiol. 2026, 313: 110874.
9. Tang M, Shu L, Xiong Y, Zhu Q, Liu Y, Huang M, Teng Q, Yuan C, Liu Q, Pan X, Zhang Z, Xu B, Shi X, Yan M, Yan D*, Li Z*. Development of a rapid detection kit for chicken infectious anemia virus nucleic acid (RPA-LFD method). J Virol Methods. 2026, 342: 115363.
10. Xu B#, Liu X#, Yan D, Teng Q, Yuan C, Zhang Z, Liu Q, Li Z. Generation and characterization of chimeric Tembusu viruses containing pre-membrane and envelope genes of Japanese encephalitis virus. Front Microbiol. 2023 Jun 22;14:1140141.
四、奖励成果
1. 获得1项新兽药证书(三类):鸭坦布苏病毒病活疫苗(FX2010-180P株),证号:(2018)新兽药证字41号,排名第六;
2. 获得1项新兽药证书(一类):鸭坦布苏病毒ELISA抗体检测试剂盒,证号(2021)新兽药证字45号,排名第五;
3. 获得2022年度上海春申金字塔杰出人才;
4. 获得2023年中国农业科学院科技进步成果奖,排名第六。
五、专利
1. 李泽君,闫大为,滕巧泱,刘芹防,苑纯秀,鸡传染性贫血病毒恒温扩增快速检测试剂盒、方法及应用,申请号:CN202511642425.7,申请时间,2025.11.11
2. 李泽君,闫大为,唐梅,刘芹防,许榜丰,苑纯秀,滕巧泱,抗鸭腺病毒3型单克隆抗体、杂交瘤细胞株及其应用,申请号:CN202511679696.X,申请时间,2025.11.17
3. 李泽君,宿鑫,闫大为,硕盾, 鸭蛋减产综合征病毒检测方法及其试剂盒ZL201811616095.4,授权时间2022年
4. 李泽君,刘芹防,闫大为,滕巧泱,苑纯秀,用于蛋白表达的真核SCV启动子及其应用,申请号:CN202410177703.5,申请时间,2024.02.08
5. 李泽君,刘芹防,闫大为,滕巧泱,苑纯秀,用于蛋白表达的真核MCV启动子及其应用,申请号:CN202410177700.1,申请时间,2024.02.08
6. 李泽君,刘芹防,闫大为,滕巧泱,苑纯秀,用于蛋白表达的真核ACV启动子及其应用 ,申请号:CN202410177697.3,申请时间,2024.02.08
7. 李泽君,潘学,刘芹防,闫大为,滕巧泱,周凡,苑纯秀,许榜丰,重组禽流感病毒灭活疫苗及其应用,申请号:CN202411639820.5,申请时间,2024.11.18
8. 李泽君,张志飞,崔利兵,苑纯秀,刘芹防,滕巧泱,闫大为,许榜丰,潘学,鸡传染性喉气管炎病毒gD蛋白单克隆抗体、其杂交瘤细胞株及应用,申请号:CN202410878971.X,申请时间,2024.07.02








