团队成员
陈兆国
职称: 研究员
学历: 博士研究生
导师类别: 博士生导师
研究方向: 食源性病原生物学及动物源性食品安全研究
一、个人简历
陈兆国,博士,研究员(专业技术三级),博士生导师,团队首席科学家。现任农业农村部动物产品质量安全生物性危害因子风险评估实验室(上海)副主任兼技术负责人,农业农村部动物寄生虫学重点实验室副主任,全国名特优新农产品(畜禽产品)全程控制技术上海中心、全国农产品质量安全与营养健康科普基地负责人,农业农村部工程建设项目评估专家,第一届全国动物病原微生物菌(毒)种保藏管理专家委员会委员,中国畜牧兽医学会兽医公共卫生学分会常务理事,中国畜牧兽医学会兽医寄生虫学分会理事,中国农学会农产品质量安全分会第二届委员会委员,中国微生物学会人兽共患病专业委员会委员,上海市免疫学会畜牧兽医免疫专业委员会副主任委员,上海市寄生虫学会理事,上海市领军人才后备队人选,中国农业科学院三级岗位杰出人才。
长期从事食源性病原生物学及动物源性食品安全研究,获得国家科技进步奖三等奖、农业部科技进步奖二等奖、上海市科技进步奖三等奖、中国农业科学院科学技术奖二等奖;参与获得新兽药证书3个。先后主持国家自然科学基金等各类课题29项,参加863等37项项目研究;培养(含联合培养)毕业及在读博士生8名、硕士生40名、博士后2名。在《Frontiers in Immunology》《Food Control》《Frontiers in Microbiology》《Applied and Environmental Microbiology》等国内外期刊发表学术论文177篇,其中SCI论文37篇,制定国家和行业标准各2项,出版专(译)著9部,授权专利6项。
二、联系方式
办公电话:021-34293157
邮 箱:zhaoguochen@shvri.ac.cn, chenzhaoguo@caas.cn
三、代表论著
[1] Sajid Ur Rahman, Haiyan Gong, Rongsheng Mi, Yan Huang, Xiangan Han and Zhaoguo Chen*. Chitosan protects immunosuppressed mice against Cryptosporidium parvum infection through TLR4/STAT1 signaling pathways and gut microbiota modulation. Frontiers in Immunology, 2022, 12: 784683.
[2] Sajid Ur Rahman, Keke Zhou, Shasha Zhou, Tiancong Sun, Rongsheng Mi, Yan Huang, Xiangan Han, Haiyan Gong*, Zhaoguo Chen*. Curcumin mitigates Cryptosporidium parvum infection through modulation of gut microbiota and innate immune-related genes in immunosuppressed neonatal mice. Microbial Pathogenesis, 2022, 164:105424.
[3] Yan Huang, Yue Song, Yanmin You, Rongsheng Mi, Xiangan Han, Haiyan Gong, Zhaoguo Chen*, Yongjie Liu*. Development of an immunocompetent mouse model susceptible to Cryptosporidium tyzzeri infection. Parasite Immunology, 2021, 43: e12800.
[4] Yehua Zhang1, Jianhua Xie1, Rongsheng Mi, Hongquan Ling, Lu Luo, Haiyan Jia, Xiaoli Zhang, Yan Huang, Haiyan Gong, Xiangan Han, Zheng Zeng*, Zhaoguo Chen*. Molecular detection and genetic characterization of Toxoplasma gondii in pork from Chongqing, southwest China. Acta Tropica, 2021, 224: 106134.
[5] Yan Zhang, Rongsheng Mi, Lijuan Yang, Haiyan Gong, Chunzhong Xu, Yongqi Feng, Xinsheng Chen, Yan Huang, Xiangan Han and Zhaoguo Chen*. Wildlife is a potential source of human infections of Enterocytozoon bieneusi and Giardia duodenalis in Southeastern China. Frontiers in Microbiology, 2021, 12: 692837.
[6] Tao Sun1, Sajid Ur Rahman1, Jinzhong Cai, Jiangyong Zeng, Rongsheng Mi, Yehua Zhang, Haiyan Gong, Hongcai Ma, Yan Huang, Xiangan Han, Quan Zhao*, Zhaoguo Chen*. Seroprevalence and associated risk factors of Toxoplasma gondii infection in yaks (Bos grunniens) on the Qinghai-Tibetan Plateau of China. Parasite, 2021, 28: 43.
[7] Xu Wang, Haiyan Jia, Haiyan Gong, Yan Zhang, Rongsheng Mi, Yehua Zhang, Xiangan Han, Zhaoguo Chen*. Expression and functionality of allergenic genes regulated by simulated gastric juice in Anisakis pegreffii. Parasitology International, 2021, 80: 102223.
[8] Xiaoli Zhang1, Rongsheng Mi1, Yehua Zhang, Shijie Zhang, Tao Sun, Haiyan Jia, Yan Huang, Haiyan Gong, Xiangan Han, Zhaoguo Chen*. Low prevalence of spargana infection in farmed frogs in the Yangtze River Delta of China. Infection, Genetics and Evolution, 2020, 85: 104466.
[9] Yehua Zhang1, Rongsheng Mi1, Yan Huang, Luming Xia, Yushu Cai, Haiyan Jia, Xiaoli Zhang, Heng Yang, Xu Wang, Xiangan Han, Zhaoguo Chen*. Molecular detection and genetic characterization of Toxoplasma gondii in pork in Shanghai, China. Food Control, 2019, 99: 57–63.
[10] Rongsheng Mi, Xiaojuan Wang, Yan Huang, Guodong Mu, Yehua Zhang, Haiyan Jia, Xiaoli Zhang, Heng Yang, Xu Wang, Xiangan Han, Zhaoguo Chen*. Sheep as a potential source of zoonotic cryptosporidiosis in China. Applied and Environmental Microbiology, 2018, 84: e00868-18.
四、代表专利标准
[1] 猪源附红细胞体荧光定量PCR检测试剂盒及其应用.授权公告日:2018.05.18,中国,ZL201410150317.3.
[2] 一种弓形虫病间接ELISA诊断试剂盒.授权公告日:2018.08.03,中国,ZL201710098062.4.
[3] 一种附红细胞体重组表位抗原及其免疫检测试剂盒.授权公告日:2019.05.31,中国,ZL201610187839.X.
[4] 禽致病性大肠杆菌等的多重PCR检测引物组、方法及试剂盒.授权日:2021.07.16,中国,ZL201810317451.6.
[5] 隐孢子虫套式PCR检测方法. 国家标准GB/T 35942-2018.
[6] 动物球虫病诊断技术. 国家标准GB/T 18647-2020.
[7] 动物源性食品中住肉孢子虫检测方法. 农业行业标准NY/T 4031-2021.
[8] 隐孢子虫卵囊检测技术——改良抗酸染色法. 农业行业标准NY/T 1949-2010.
五、奖励成果
[1] 国家科技进步奖三等奖、农业部科学技术进步奖二等奖,地克珠利(Diclazuril)的研制与开发,史天卫、孙晓泉、徐庆梅、吴薛忠、黄兵、张丽芳、陈贻顺、张仓、翟良、黄伟华、赵其平、费陈忠、盛成德、陈兆国、裘敏琪、叶明忠、金锡禄,1999(国家奖)、1998(部奖).
[2] 中国农业科学院科学技术二等奖,地克珠利溶液的研究与开发,徐庆梅、张丽芳、吴薛忠、盛成德、裘敏琪、赵其平、翟良、费陈忠、陈兆国、黄伟华,2000.
[3] 上海市科学技术进步奖三等奖,集约化养鸡球虫抗药性监测技术的推广应用,黄兵、赵其平、陈燕军、陈兆国、陆佰君、吴薛忠、史天卫、钱才根、范正清、陈慈中、叶明忠、郑彩英、徐永根、张文秀、黄福珍、夏爱萍,2003.
[4] 地克珠利(原料),(97)新兽药证字第03号,1997.
[5] 地克珠利预混剂0.5%,(97)新兽药证字第04号,1997.
[6] 地克珠利溶液0.5%,(99)新兽药证字第04号,1999.