团队成员
韩先干
职称: 研究员
学历: 博士研究生
导师类别: 博士生导师
研究方向: 病原微生物致病机制、疫苗和基于人工智能技术开展动物疫病防控技术
一、个人简历
韩先干,博士,研究员,博士生导师,南京农业大学、山西农业大学校外博导。长期从事病原微生物致病机制、疫苗和基于人工智能技术开展动物疫病防控技术研究。主持国家重点研发计划(政府间国际合作)项目1项,国家自然科学基金项目5项,上海科委、农委项目5项。培养(含联合培养)硕士、博士50余名。在《Nature Communications》《Journal of Bacteriology》《中国农业科学》等期刊发表论文210篇(SCI论文100余篇),获专利授权25项。
二、联系方式
办公电话:021-54225517
邮 箱:hanxgan@shvri.ac.cn
三、代表论著
[1] Jiangang Hu, Yi Gu, Huiqi Lu, Muhammad Akmal Raheem, Fangheng Yu, Xiangpeng Niu, Jiakun Zuo, Huifang Yin, Cuiqin Huang, Saqib Nawaz, Xiangjun Song, Jian Tu, Wen Zhou, Wei Jiang, Zhaoguo Chen, Xiangan Han *, Kezong Qi *. Identification of novel biofilm genes in avian pathogenic Escherichia coli by Tn5 transposon mutant library. World journal of microbiology & biotechnology, 2022, 38(8): 130.
[2] Jiangang Hu, Chuanyan Che, Wei Jiang, Zhaoguo Chen, Jian Tu, Xiangan Han * and Kezong Qi*. Avian pathogenic Escherichia coli through Pfs affects the tran-scription of membrane proteins to resist ß-lactam antibiotics. Veterinary sciences, 2022, 9(3): 98.
[3] Jiangang Hu,Xiaolong Lv,Xiangpeng Niu,Fangheng Yu,Jiakun Zuo,Yinli Bao,Huifang Yin,Cuiqin Huang,Saqib Nawaz,Wen Zhou,Wei Jiang,Zhaoguo Chen,Jian Tu, Kezong Qi * and Xiangan Han *. Effect of nutritional and environmental conditions on biofilm formation of avian pathogenic Escherichia coli . Journal of applied microbiology, 2022, 132(6): 4236-4251.
[4] Xudong Wang, Xinguang Lin, Zhixin Wan, Shaohui Wang, Jiakun Zuo, Zhihao Wang, Yuanyuan Xu, Xiangan Han*, Jinfeng Miao*. The deletion of yeaJ gene facilitates Escherichia coli escape from immune recognition. Journal of Bacteriology, 2021, 203(20): e0033621.
[5] Xudong Wang, Xinguang Lin, Zhixin Wan, Jiakun Zuo, Zhihao Wang, Yuanyuan Xu, Xiangan Han*, Jinfeng Miao*. Regulation of ydiV -induced biological characteristics permits Escherichia coli evasion of the host STING inflammatory response. Veterinary Microbiology, 2021, 261:109207.
[6] Yawei Jing, Jiakun Zuo, Phouthapane Vanhnaseng, Zhaoguo Chen*, Xiangan Han*. An optimized method for detecting AI-2 signal molecule by a bioassay with Vibrio harveyi BB170. Microbiology, 2021, 90(3): 383-391.
[7] Jiangang Hu, Chuanyan Che, Jiakun Zuo , Xiangpeng Niu , Zhihao Wang , Liyan Lian , Yuanzheng Jia , Haiyang Zhang , Tao Zhang , Fangheng Yu , Saqib Nawaz and Xiangan Han *. Effect of antibiotics on the colonization of live attenuated Salmonella e nteritidis vaccine in chickens. Frontiers in Veterinary Science, 2021, 8: 784160.