一、个人简介

邓磊，博士，所聘研究员，国家级海外引进青年人才，上海市浦江人才。 2018 – 2021年获得四川农业大学和新加坡国立大学联合培养博士学位。2021 – 2025年先后在新加坡国立大学和哈佛大学医学院进行博士后研究。2025年4月加入中国农业科学院上海兽医研究所，聘为所级青年英才。主要从事肠道微生物与宿主黏膜免疫互作机制研究，近年来在“肠道菌群–代谢物–免疫轴”调控机制研究方面取得了一系列创新性成果，以第一作者或通讯作者在 The Lancet Microbe（2025）、Signal Transduction and Targeted Therapy（2025）、Advanced Sciences（2025）、Gut Microbes（2024）、Theranostics（2023）、NPJ Biofilms and Microbiomes（2023）、Cellular and Molecular Life Sciences（2022）、Plos Pathogens（2021）等国际权威期刊发表多篇论文。入选斯坦福大学和爱思唯尔全球前 2% 顶尖科学家榜单，担任iMeta、Research、Med Research、Cell Proliferation等国际期刊青年编委。主持国家海外高层次引才项目、国家自然科学基金青年科学基金项目（C类）、上海市农业科技创新重点研发项目、中央级公益性科研院所基本科研业务费专项资金项目等。

二、联系方式

办公电话：19121061233

邮箱：ldeng@shvri.ac.cn

三、代表论著

1. Lei Deng; Kevin Shyong Wei Tan; From parasite to partner: unraveling the multifaceted role of Blastocystis in human health and disease. The Lancet Microbe. 2025;6(9):101155.

2. Lei Deng; Kevin Shyong Wei Tan; Unveiling the hidden ally: Blastocystis links healthier diets and cardiometabolic benefits, Signal Transduction and Targeted Therapy, 2025, 10(77)

3. Lei Deng; Kevin Shyong Wei Tan ; Decoding Blastocystis-driven mechanisms in gut microbiota and host metabolism, Advanced Science, 2025. e2416325

4. Lei Deng; Lukasz Wojciech; Chin Wen Png; Dorinda Yan Qin Kioh; Yuxiang Gu; Thet Tun Aung; Benoit Malleret; Eric Chun Yong Chan; Guangneng Peng; Yongliang Zhang; Nicholas Robert John Gascoigne; Kevin Shyong Wei Tan ; Colonization with two different Blastocystis subtypes in DSSinduced colitis mice is associated with strikingly different microbiome and pathological features, Theranostics, 2023, 13(3): 1165-1179

5. Lei Deng; Shaohui Wang ; Colonization resistance: the role of gut microbiota in preventing Salmonella invasion and infection, Gut Microbes, 2024, 16(1)

6. Lei Deng; Lukasz Wojciech; Chin Wen Png; Dorinda Yan Qin Kioh; Geok Choo Ng; Eric Chun Yong Chan; Yongliang Zhang; Nicholas R. J. Gascoigne; Kevin Shyong Wei Tan ; Colonization with ubiquitous protist Blastocystis ST1 ameliorates DSS-induced colitis and promotes beneficial microbiota and immune outcomes, npj Biofilms and Microbiomes, 2023, 9(1)

7. Lei Deng; Lukasz Wojciech; Chin Wen Png; Eileen Yiling Koh; Thet Tun Aung; Dorinda Yan Qin Kioh; Eric Chun Yong Chan; Benoit Malleret; Yongliang Zhang; Guangneng Peng; Nicholas Robert John Gascoigne; Kevin Shyong Wei Tan ; Experimental colonization with Blastocystis ST4 is associated with protective immune responses and modulation of gut microbiome in a DSS-induced colitis mouse model, Cellular and Molecular Life Sciences, 2022, 79(5)

8. Lei Deng; Lukasz Wojciech; Nicholas R. J. Gascoigne; Guangneng Peng; Kevin S. W. Tan ; New insights into the interactions between Blastocystis, the gut microbiota, and host immunity, PLOS Pathogens, 2021, 17(2): e1009253

9. Lei Deng; Jonathan W. J. Lee; Kevin S.W. Tan ; Infection with pathogenic Blastocystis ST7 is associated with decreased bacterial diversity and altered gut microbiome profiles in diarrheal patients, Parasites & Vectors, 2022, 15(1): 312-312

10. Lei Deng; Kevin S. W. Tan ; Interactions between Blastocystis subtype ST4 and gut microbiota in vitro, Parasites & Vectors, 2022, 15(1)