团队成员
胡青海
职称: 研究员
学历: 博士研究生
导师类别: 博士生导师
研究方向: 鸭疫里默氏杆菌的分子致病机制、新型疫苗及食源性致病菌快速检测技术
一、个人简历
胡青海,博士,研究员,博士生导师。长期从事鸭疫里默氏杆菌的分子致病机制、新型疫苗及食源性致病菌快速检测技术的研究,获得江苏省科技进步三等奖(2002,排名第1)、教育部技术发明二等奖(2009,排名第4)和中国农科院成果成果二等奖(2014,排名第4)各1项。主持国家自然科学基金面上项目4项、国家重点研发项目子课题1项、上海市自然科学基金1项等,培养(含联合培养)博士生3名、硕士生29名。在《Journal of Biogical Chemistry》、《Veterinary Microbiology》《Veterinary Research》等国内外发表论文70篇,其中SCI论文22篇,获授权的国家发明专利6项。
二、联系方式
办公电话:021-54847327
邮 箱:hqh123@163.com
三、代表论著
1. Bingqing Sun, Yafei Xue, Xiaoli Du, Xiaohua He, Zuocheng Zou, Xiangqiang Tian, Zhonghao Hu, Haoyang Liu, Nazrul Islam, Qinghai Hu*. Identification of genetic determinants of hemolytic activity of Riemerella anatipestifer using random transposon mutagenesis, Veterinary Research, 2021, 52(1):19
2. Minjie Tao, Jialing Wang, Ke Li, Yafei Xue, Xinxin Xu, Xiaoli Du, Xiaohua He, Xiangqiang Tian, Zuocheng Zou, Zhonghao Hu, Nazrul Islam, Qinghai Hu*. Development of signature-tagged mutagenesis in Riemerella anatipestifer to identify genes essential for survival and pathogenesis, Veterinary Microbiology, 2020, 250:108857.
3. Yanshan Gong, Yongsheng Yang, Yan Chen, Bingqing Sun, Yafei Xue, Xinxin Xu, Xi Wang, Nazrul Islam, Xiaoli Du, Qinghai Hu*. Characterization of the hemolytic activity of Riemerella anatipestifer, Microbiology-SGM, 2020, 166(5):436-439.
4. Xinxin Xu#, Yaohui Xu#, Shuang Miao, Pan Jiang, Junsheng Cui, Yanshan Gong, Panpan Tan, Xiaoli Du, Nazrul Islam, Qinghai Hu*. Evaluation of the protective immunity of Riemerella anatipestifer OmpA, Appllied Microbiology and Biotechnology, 2020, 104(3):1273-1281.
5. Tao Zheng, Pan Jiang, Bo Cao, Qiuxiang Cheng, Lingxin Kong, Xiaoqing Zheng, Qinghai Hu*, Delin You*. DndEi exhibits helicase activity essential for DNA phosphorothioate modification and ATPase activity strongly stimulated by DNA substrate with a GAAC/GTTC motif, Journal of Biological Chemistry, 2016, 291(3): 1492-1500.
6. Xintao Ni, Pan Jiang, Linlin Xing, Changcan Ou, Hui Yu, Jingjing Qi, Bingqing Sun, Junsheng Cui, Guijun Wang*, Qinghai Hu*. Genome-wide mining of potential virulence-associated genes in Riemerella anatipestifer using random transposon mutagenesis, Veterinary Microbiology, 2016, 189:52-58.
7. Linlin Xing, Hui Yu, Jingjing Qi, Pan Jiang, Bingqing Sun, Junsheng Cui, Changcan Ou, Weishan Chang*, Qinghai Hu*. ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer. PLos One, 2015, 10(6):e0131078.
8. Jing Tu, Fengying Lu, Shuang Miao, Xintao Ni, Pan Jiang, Hui Yu, Linlin Xing, Shengqing Yu, Chan Ding, Qinghai Hu*. The siderophore-interacting protein is involved in iron acquisition and virulence of Riemerella anatipestifer strain CH3. Veterinary Microbiology,2014, 168: 395-402.
9. Fengying Lu, Shuang Miao, Jing Tu, Xintao Ni, Linlin Xing, Hui Yu, Ling Pan, Qinghai Hu*. The role of TonB dependent receptor TbdR1 in Riemerella anatipestifer in iron acquisition and virulence. Veterinary Microbiology,2013, 167: 713-718.
10. Qinghai Hu*, Shuang Miao, Xintao Ni, Fengying Lu, Hui Yu, Linlin Xing, Pan Jiang. Construction of a shuttle vector for use in Riemerella anatipestifer. Journal of Microbiological Methods,2013, 95: 262–267.
四、专利标准
1. 一种鸭疫里默氏杆菌-大肠杆菌穿梭表达载体及其构建方法和应用, 2015-2-4, 中国, ZL201210100921.6
2. 一种鸭源常见细菌多重PCR检测试剂盒及其检测方法, 2012-11-7, 中国, ZL201110093695.9
五、奖励成果
1. 江苏省科技进步三等奖,鸭疫里默氏杆菌病防制方法的研究,胡青海、刘晓文、丁铲、张知良、黄建芳、李刚、刘岳龙、苗晋锋、赵宝华、徐步、王晓泉、刘华雷、章耀良.2002年。
2. 教育部技术发明二等奖, 非抗性筛选DNA疫苗载体及沙门氏菌运送系统,焦新安、潘志明、张晓明、胡青海、黄金林、刘秀梵、唐丽华、张小荣、孙林、殷月兰、焦凤超、张辉、程宁宁、刘丽平. 2009年。
3. 中国农业科学院科技成果二等奖,鸭疫里默氏杆菌毒力基因、诊断技术研究及应用,于圣青、丁铲、韩先干、胡青海、王小兰等,2014。