蒋 蔚

一、个人简历

蒋蔚，博士，研究员，硕士生导师。长期从事人畜共患病病原的致病机理和新型诊断技术的研究。 获得上海市科学进步奖、中国检验检疫学会科技奖、上海市浦东新区科学进步奖、中华人民共和国上海海关科技兴检奖等奖项。获“上海市巾帼建功标兵”荣誉称号。主持国家自然基金、上海市科学委员会计划项目等17个项目，培养（含联合培养）硕士生20名。以第一或通讯作者论文在《Biosensors and Bioelectronics》《Food Control》《Applied microbiology and Biotechnology》等国内外杂志上发表论文45篇，出版专著1部，获专利7项，科技成果认证3项，形成行业标准2项。

二、联系方式

办公电话：021-34293397

邮       箱：jiangwei@shvri.ac.cn

三、教育经历

2000.09-2004.06  扬州大学  动物医学  学士

2004.09-2007.06  南京农业大学  预防兽医专业  硕士

2010.09-2014.06  南京农业大学  预防兽医专业  博士

四、工作经历

2007.08-2009.12  中国农科院上海兽医研究所  研究实习员

2010.01-2015.12  中国农科院上海兽医研究所  助理研究员

2016.01-2021.12  中国农科院上海兽医研究所  副研究员

2022.01-至今  中国农科院上海兽医研究所  研究员

五、代表论著

[1] Yangyang Li , Weidong Sun , Quan Wang, Ying Yu, Ying Wan, Kai Zhou, Rong Guo ,Xiangan Han, Zhaoguo Chen , Weihuan Fang , Wei Jiang*. The GntR-like transcriptional regulator HutC involved in motility, biofilm-forming ability, and virulence in  Vibrio parahaemolyticus . Microbial Pathogenesis, 2022, 167: 105546

[2] Wei Jiang, Yaling Ren, Xiangan Han, Tongling Shan, Junxin Xue, Zhaoguo Chen, Yongjie Liu, Quan Wang. Recombinase polymerase amplification-lateral flow (RPA-LF) assay combined with immunomagnetic separation for rapid visual detection of  Vibrio parahaemolyticus  in raw oysters. Analytical and Bioanalytical Chemistry, 2020, 412(12): 2903-2914.

[3] Wei Jiang, Xiangan Han, Quan Wang, Xintong Li, Li Yi, Yongjie Liu*, Chan Ding*.  Vibrio parahaemolyticus  enolase is an adhesion-related factor that binds plasminogen and functions as a protective antigen. Applied microbiology and Biotechnology, 2014, 98 (11): 4937-4948.

[4] Quan Wang, Mengyao Long, Caiyun Lv, Sipei Xin, Xiangan Han, Wei Jiang* . Lanthanide-labeled fluorescent-nanoparticle immunochromatographic strips enable rapid and quantitative detection of  Escherichia coli  O157:H7 in food samples. Food Control, 2020, 109: 106894.  

[5] Yun Chen, Qi Liu, Jun-Xin Xue, Man-Yu Zhang, Xiao-Ling Geng, Quan Wang* and Wei Jiang*. Genome-wide CRISPR/Cas9 screen identifies new genes critical for defense against oxidant stress in  Toxoplasma gondii.  Frontiers in Microbiology, 2021, 12: 670705.

[6] Wei Jiang, Yingchun Liu, Yongjun Chen, Peter Chun, Kailing Yao, Xiangan Han, Shaohui Wang, Shengqing Yu, Yongjie Liu*, Quan Wang*. A novel dynamic flow immunochromatographic test (DFICT) using gold nanoparticles for the serological detection of  Toxoplasma gondii  infection in dogs and cats. Biosensors and Bioelectronics, 2015, 72: 133–139.

[7] Wei Jiang, Jun-Xin Xue, Ying-Chun Liu, Tao Li, Xian-Gan Han, Shao-Hui Wang, Yong-Jun Chen, Jingjing Qi, Sheng-Qing Yu*, Quan Wang*. Identification and characterization of an immunogenic antigen, enolase 2, among excretory/secretory antigens (ESA) of  Toxoplasma gondii . Protein Expression and Purification, 2016, 127: 88-97.

[8] Wei Jiang, Yan Wang, Yingchun Liu, Tao Li, Shaohui Wang, Xiangan Han, Quan Wang. Seroepidemiological study of canine  Leishmania infantum  and  Toxoplasma gondii  infections in Shanghai, China, and analysis of risk factors. Annals of Agricultural and Environmental Medicine, 2016, 23(3): 420–424.

[9] Quan Wang, Yingchun Liu, Mingyan Wang,Yongjun Chen and Wei Jiang*. A multiplex immunochromatographic test using gold nanoparticles for the rapid and simultaneous detection of four nitrofuran metabolites in fish samples. Analytical and Bioanalytical Chemistry, 2018, 410(1): 223-233.    

[10] Yuanyuan Shi¹, Wei Jiang¹, Zhiyong Ma and Yafeng Qiu*. A case report of pulmonary tritrichomonosis in a pig. BMC Veterinary Research, 2017, 13(1): 348.

六、专利标准

[1] 蒋蔚，王权，刘永杰，韩先干，任亚玲. 一种用于检测副溶血弧菌的试剂盒、引物对、探针和方法. 授权公告日：2020.06.19，中国，ZL201910281743.3.

[2] 蒋蔚，韩先干，王权，王亚磊，张海洋. 抗金黄色葡萄球菌单克隆抗体、应用及包含其的免疫磁珠. 授权公告日：2022.03.03，中国，ZL20211072909.8.

[3] 蒋蔚，王权，薛俊欣，刘迎春，陈永军，宫枫举，白雪瑞，曾鹏. 一种检测弓形虫急性感染的方法及其靶标蛋白. 授权公告日：2017.02.08，中国，ZL201510271816.2.

[4] 蒋蔚，王权，陈永军，刘迎春，史子学，马志永，顾惠明，杨康，宋宁宁，石金磊，李欣彤. 一种抗流感病毒的单链抗体及其制备方法和应用. 授权公告日：2014.06.04，中国，ZL201210063870.4.

[5] 王权，薛俊欣，蒋蔚，陈永军，刘迎春，王民燕，宫枫举，程军霞. 一种高效检测弓形虫急性感染的方法及其靶标蛋白. 授权公告日：2017.06.27，中国，ZL20151 0272187.5.

[6] 韩先干，王志豪，祁克宗，左佳坤，龚建森，苗晋锋，陈兆国，蒋蔚，王少辉，米荣升，黄燕. 禽致病性大肠杆菌等的多重PCR检测引物组、方法及试剂盒. 授权公告日：2021.07.16，中国，ZL201810317451.6.

[7] 王艳、蒋蔚、黄忠荣、王权、熊炜、李健. 水生动物副溶血弧菌和霍乱弧菌双重实时荧光检测方法. 出入境检验检疫行业标准SN/T5125-2019.

七、奖励成果

[1] 上海市科学进步奖三等奖，动物疫病和动物源性食品安全防控检测中新技术的开发与应用，第2完成人，证书编号：20174200-3-R02.

[2] 上海出入境检验检疫局科技兴检奖三等奖，弓形虫病快速检测方法的研究与应用，第2完成人，证书编号：2017-028-3-R02.