首页» 人才队伍» 猪呼吸道传染病团队

人才队伍

李蓓蓓


研究领域:动物源细菌耐药性
电话:021-34510616
电子邮件:lbb@shvri.ac.cn

简历:
李蓓蓓,男,1984年11月出生,副研究员,硕士研究生导师。2006年毕业于山西农业大学,获农学学士学位,2011年毕业于中国农业大学,获农学博士学位。2011年至今在中国农业科学院上海兽医研究所工作,2015年6月至2016年9月在美国加州大学戴维斯分校做访问学者,2017年9月至2017年12月在丹麦哥本哈根大学访学进修。主要从事动物源细菌耐药性流行病学、新耐药机制解析、重要耐药基因的传播分子机理以及耐药快速检测技术的开发应用。在“Journal of Antimicrobial Chemotherapy”和“Veterinary Microbiology”等主流学术杂志发表SCI论文30余篇,其中第一或者通讯作者13篇。国际期刊Journal of Antimicrobial Chemotherapy、Journal of global antimicrobial resistance、Foodborne pathogens and disease、Veterinary Microbiology、Plos One等杂志审稿专家。2017年入选中国农业科学院青年英才培育工程(所级),2018年受英国政府邀请参加Wilton Park国际政策研讨会,2019年入选上海市青年科技启明星。


科研项目:
1、主持项目:国家自然基金面上项目“SXT/R391元件在动物源细菌中的流行、进化及其与细菌毒力的关联性”,62万元,2017年1月-2020年12月
2、主持项目:国家自然基金青年基金“截短侧耳类抗菌药物的新耐药机制解析及其传播机理研究”,25万元,2014年1月-2016年12月
3、主持项目:上海市科技人才计划项目“重要耐药基因在动物肠道微生物群落中的分布和传播扩 散研究”,40万元,2019年4月-2022年3月
4、主持项目:中国农科院基本业务费增量项目“猪呼吸道病原菌耐药机制及其传播分子机理的研究”,20万元,2016年9月-2018年9月
5、主持项目:所基本科研业务费“金黄色葡萄球菌对截短侧耳类抗生素的耐药机制研究”,20万元, 2012年1月至2013年12月
6、主持项目:所基本科研业务费“临床分离副猪嗜血杆菌耐药性调查及耐药机制研究”,20万元,2014年1月至2015年12月
7、主持项目:横向课题“江浙沪畜禽及其产品病原菌分离和耐药性检测”,22万元,2012年1月-2016年12月


代表性文章:
1.Huixian Tong,Juxiang Liu,Xiaohui Yao,Haiyan Jia,Jianchao Wei, Donghua Shao, Ke Liu, Yafeng Qiu, Zhiyong Ma, Beibei Li High carriage rate of mcr-1 and antimicrobial resistance profiles of mcr-1-positive Escherichia coli isolates in swine faecal samples collected from eighteen provinces in China. Veterinary microbiology 2018, 225, 53-57. (Corresponding author)
2.Beili Huan, Ke Liu, Yuming Li, Jianchao Wei, Donghua Shao, Yuanyuan Shi, Yafeng Qiu, Beibei Li and Zhiyong Ma. Porcine serum amyloid A3 is expressed in extrahepatic tissues and facilitates viral replication during porcine respiratory and reproductive syndrome virus infection. Developmental and comparative immunology. 2018;79:51-58. (Co-corresponding author)
3.Jinpeng Xu, Haiyan Jia, Guanghui Cui, Huixian Tong, Jianchao Wei, Donghua Shao, Ke Liu, Yafeng Qiu, Beibei Li and ZhiyongMa. ICEAplChn1, a novel SXT/R391 integrative conjugative element (ICE), carrying multiple antibiotic resistance genes in Actinobacillus pleuropneumoniae, Veterinary Microbiology, 2018. 220:18-23. (Co-corresponding author)
4.Beibei Li, Jiannan Yao, Jinachao Wei, Donghua Shao, Ke Liu, Yafeng Qiu and Zhiyong Ma. Characterization of fluoroquinolone resistance in methicillin-resistant Staphylococcus aureus of human and pig origin. Journal of global antimicrobial resistance. 2018. 12: 77-78.
5.Beibei Li, Licai Ma, Yingli Li, Haiyan, Jia, Jianchao Wei, Donghua Shao, Ke Liu, Yuanyuan Shi, Yafeng Qiu and Zhiyong Ma. Antimicrobial Resistance of Campylobacter Species Isolated from Broilers in Live Bird Markets in Shanghai, China. Foodborne pathogens and disease. 2017. 14: 96-102
6.Beibei Li, Yue Zhang, Jianchao Wei, Donghua Shao, Ke Liu, Yuanyuan Shi, Yafeng Qiu and Zhiyong Ma. Characterization of a novel small plasmid carrying the florfenicol resistance gene floR in Haemophilus parasuis. Journal of Antimicrobial Chemotherapy.  2015. 70 (11):3159-3161.
7.Beibei Li, Sarah Wendlandt, Jiannan Yao, Yiqiu Liu, Qing Zhang, Zixue Shi, Jianchao Wei, Donghua Shao, Stefan Schwarz, Shaohui Wang and Zhiyong Ma. Detection and new genetic environment of the pleuromutilin–lincosamide–streptogramin A resistance gene lsa(E) in methicillin-resistant Staphylococcus aureus of swine origin. Journal of Antimicrobial Chemotherapy. 2013.68 (6):1251-1255.  
8.Beibei Li, Congming Wu, Yang Wang and Jianzhong Shen. Single and dual mutations at positions 2058, 2503 and 2504 of 23S rRNA and their relationship to resistance to antibiotics that target the large ribosomal subunit. Journal of Antimicrobial Chemotherapy. 2011. 66(9):1983-1986.  
9.Beibei Li, Jianzhong Shen, Xingyuan Cao, Yang Wang, Lei Dai, Siyang, Huang and Congming Wu. Mutations in 23S rRNA gene associated with decreased susceptibility to tiamulin and valnemulin in Mycoplasma gallisepticum. FEMS Microbiology Letters. 2010. 308(2):144-149.  
10.Jun Li†, Beibei Li† (Co-first authors), SarahWendlandt, Stefan Schwarz, YangWang, Congming Wu, Zhiyong Ma and Jianzhong Shen. Identification of a novel vga(E) gene variant that confers resistance to pleuromutilins, lincosamides and streptogramin A antibiotics in staphylococci of porcine origin. Journal of Antimicrobial Chemotherapy. 2014. 69 (4): 919-923.  
11.Sarah Wendlandt †, Beibei Li †(Co-first authors), Zhiyong Ma and Stefan Schwarz. Complete sequence of the multi-resistance plasmid pV7037 from a porcine methicillin-resistant Staphylococcus aureus. Veterinary Microbiology. 2013. 166: 650-654.
12.Sarah Wendlandt, Beibei Li, Carmen Lozano, Zhiyong Ma, Carmen Torres and Stefan Schwarz. Identification of the novel spectinomycin resistance gene spw in methicillin-resistant and methicillin-susceptible Staphylococcus aureus of human and animal origin. Journal of Antimicrobial Chemotherapy. 2013. 68 (7): 1679-1680.
13.Sarah Wendlandt, Jianzhong Shen, Kristina Kadlec, Yang Wang, Beibei Li, Wan-Jiang Zhang, Andrea T. Feßler, Congming Wu, Stefan Schwarz. Multidrug resistance genes in staphylococci from animals that confer resistance to critically and highly important antimicrobial agents in human medicine. Trends in Microbiology. 2015. 23: 44-54.
14.Lei Dai, Congming Wu, Minggui Wang, Yang Wang, Siyang Huang, Lining Xia, Beibei Li and Jianzhong Shen. First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. Antimicrobial Agents and Chemotherapy. 2010. 54: 3953-3955.
15.Lei Dai, Liming Lu, Congming Wu, Beibei Li, Siyang Huang, Shaochen Wang, Yonghua Qi and Jianzhong Shen. Characterization of antimicrobial resistance among Escherichia coli isolates from chickens in China between 2001 and 2006. FEMS microbiology letters. 2008. 286: 178-183.
16.Siyang Huang, Xingquan Zhu, Yang Wang, Hebing Liu, Lei Dai, Jiangkang He, Beibei Li, Congming Wu and Jianzhong Shen. Co-carriage of qnrS1, floR, and blaCTX-M-14 on a Multidrug-Resistant Plasmid in Escherichia coli Isolated from Pigs. Foodborne Pathogens and Disease. 2012. 9(10): 896-901.